lncRNA H19/miR‐675 axis represses prostate cancer metastasis by targeting TGFBI

Prostate cancer is a leading cause of cancer‐related mortality in men worldwide and there is a lack of effective treatment options for advanced (metastatic) prostate cancer. Currently, limited knowledge is available concerning the role of long non‐coding RNAs in prostate cancer metastasis. In this s...

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Veröffentlicht in:	The FEBS journal 2014-08, Vol.281 (16), p.3766-3775
Hauptverfasser:	Zhu, Miaojun, Chen, Qin, Liu, Xin, Sun, Qian, Zhao, Xian, Deng, Rong, Wang, Yanli, Huang, Jian, Xu, Ming, Yan, Jianshe, Yu, Jianxiu
Format:	Artikel
Sprache:	eng
Schlagworte:	3' Untranslated Regions Base Sequence Binding Sites Bone Neoplasms - genetics Bone Neoplasms - metabolism Bone Neoplasms - secondary Cell adhesion & migration Cell Line, Tumor Cell Movement Epithelial Cells - physiology Extracellular Matrix Proteins - genetics Extracellular Matrix Proteins - metabolism Gene Expression Regulation, Neoplastic Humans lncRNA H19 Male Medical research Metastasis MicroRNAs - genetics miR‐675 Prostate - pathology Prostate cancer Prostatic Neoplasms - genetics Prostatic Neoplasms - metabolism Prostatic Neoplasms - pathology Ribonucleic acid RNA RNA Interference RNA, Long Noncoding - genetics RNA, Messenger - genetics TGFBI Transforming Growth Factor beta - genetics Transforming Growth Factor beta - metabolism tumor metastasis
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