Value of liver elastography and abdominal ultrasound for detection of complications of allogeneic hemopoietic SCT
Hepatic complications contribute to morbidity and mortality after allogeneic hemopoietic SCT. Liver Doppler ultrasound and elastography represent promising methods for pretransplant risk assessment and early detection of complications. Ultrasound (liver and spleen size, liver perfusion) and elastogr...
Gespeichert in:
| Veröffentlicht in: | Bone marrow transplantation (Basingstoke) 2014-06, Vol.49 (6), p.806-811 |
|---|---|
| Hauptverfasser: | , , , , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 811 |
|---|---|
| container_issue | 6 |
| container_start_page | 806 |
| container_title | Bone marrow transplantation (Basingstoke) |
| container_volume | 49 |
| creator | Karlas, T Weber, J Nehring, C Kronenberger, R Tenckhoff, H Mössner, J Niederwieser, D Tröltzsch, M Lange, T Keim, V |
| description | Hepatic complications contribute to morbidity and mortality after allogeneic hemopoietic SCT. Liver Doppler ultrasound and elastography represent promising methods for pretransplant risk assessment and early detection of complications. Ultrasound (liver and spleen size, liver perfusion) and elastography (transient elastography (TE); right liver lobe acoustic radiation force impulse imaging (r-ARFI); left liver lobe ARFI (l-ARFI)) were prospectively evaluated in patients with indications for allo-SCT. Measurements were performed before and repeatedly after SCT. Results were compared with the incidence of life-threatening complications and death during the first 150 days after SCT. Of 59 included patients, 16 suffered from major complications and 9 of them died within the follow-up period. At baseline, liver and spleen size, liver perfusion, TE and r-ARFI did not differ significantly between patients with and without severe complications. In contrast, l-ARFI was significantly elevated in patients who later developed severe complications (1.58±0.30 m/s vs 1.37±0.27 m/s,
P
=0.030). After SCT, l-ARFI values remained elevated and TE showed increasing liver stiffness in patients with complications. The value of conventional liver ultrasound for prediction of severe SCT complications is limited. Increased values for TE and l-ARFI are associated with severe SCT complications and demand further evaluation. |
| doi_str_mv | 10.1038/bmt.2014.61 |
| format | Article |
| fullrecord | <record><control><sourceid>gale_proqu</sourceid><recordid>TN_cdi_proquest_miscellaneous_1554952584</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><galeid>A372883343</galeid><sourcerecordid>A372883343</sourcerecordid><originalsourceid>FETCH-LOGICAL-c543t-996898adc8200fb56b4fcf3e805b00261c5cff387172c4d0c878ee6ed27f9de03</originalsourceid><addsrcrecordid>eNqNkk1v1DAQhiMEotvCiTuKhFohQRZ_xzlWK76kShwoXC3HGe-6cuLUTpD673HYhbaoQsgH2-NnZjSv36J4gdEaIyrftf20JgiztcCPihVmtag4FfxxsUJEyIpS0RwVxyldoQwxxJ8WR4TVGHFRr4rr79rPUAZbevcDYglepylsox53N6UeulK3XejdoH05-ynqFOYctCGWHUxgJheGJdmEfvTO6OWeloD2PmxhAGfKHfRhDA6mfP66uXxWPLHaJ3h-2E-Kbx_eX24-VRdfPn7enF9UhjM6VU0jZCN1ZyRByLZctMwaS0Ei3qI8GDbcWEtljWtiWIeMrCWAgI7UtukA0ZPi9b7uGMP1DGlSvUsGvNcDhDkpzDlrOOGS_QdKScMxqUlGX_2FXoU5ZnmSIoIRwrFomn9RuRZuapnHuKW22oNygw1ZYLO0Vue0JlJSymim1g9QeXXQOxMGsC7H7yWc3UnYgfbTLgU___qb--CbPWhiSCmCVWN0vY43CiO1WEtla6nFWkrgTL88zDS3PXR_2N9eysDpAdDJaG-jHoxLt5zkNDde1H6751J-GrYQ74jzQN-fGtziKw</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1531978805</pqid></control><display><type>article</type><title>Value of liver elastography and abdominal ultrasound for detection of complications of allogeneic hemopoietic SCT</title><source>MEDLINE</source><source>Nature</source><source>EZB-FREE-00999 freely available EZB journals</source><source>SpringerLink Journals - AutoHoldings</source><creator>Karlas, T ; Weber, J ; Nehring, C ; Kronenberger, R ; Tenckhoff, H ; Mössner, J ; Niederwieser, D ; Tröltzsch, M ; Lange, T ; Keim, V</creator><creatorcontrib>Karlas, T ; Weber, J ; Nehring, C ; Kronenberger, R ; Tenckhoff, H ; Mössner, J ; Niederwieser, D ; Tröltzsch, M ; Lange, T ; Keim, V</creatorcontrib><description>Hepatic complications contribute to morbidity and mortality after allogeneic hemopoietic SCT. Liver Doppler ultrasound and elastography represent promising methods for pretransplant risk assessment and early detection of complications. Ultrasound (liver and spleen size, liver perfusion) and elastography (transient elastography (TE); right liver lobe acoustic radiation force impulse imaging (r-ARFI); left liver lobe ARFI (l-ARFI)) were prospectively evaluated in patients with indications for allo-SCT. Measurements were performed before and repeatedly after SCT. Results were compared with the incidence of life-threatening complications and death during the first 150 days after SCT. Of 59 included patients, 16 suffered from major complications and 9 of them died within the follow-up period. At baseline, liver and spleen size, liver perfusion, TE and r-ARFI did not differ significantly between patients with and without severe complications. In contrast, l-ARFI was significantly elevated in patients who later developed severe complications (1.58±0.30 m/s vs 1.37±0.27 m/s,
P
=0.030). After SCT, l-ARFI values remained elevated and TE showed increasing liver stiffness in patients with complications. The value of conventional liver ultrasound for prediction of severe SCT complications is limited. Increased values for TE and l-ARFI are associated with severe SCT complications and demand further evaluation.</description><identifier>ISSN: 0268-3369</identifier><identifier>EISSN: 1476-5365</identifier><identifier>DOI: 10.1038/bmt.2014.61</identifier><identifier>PMID: 24710567</identifier><identifier>CODEN: BMTRE9</identifier><language>eng</language><publisher>London: Nature Publishing Group UK</publisher><subject>631/250/1904 ; 692/699/1503/1607 ; 692/700/1421 ; 692/700/565/2194 ; Abdomen - diagnostic imaging ; Adult ; Aged ; Allografts ; Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy ; Biological and medical sciences ; Bone marrow ; Bone marrow, stem cells transplantation. Graft versus host reaction ; Cell Biology ; Cohort Studies ; Complications ; Doppler effect ; Elasticity Imaging Techniques - methods ; Evaluation ; Female ; Graft vs Host Disease - diagnostic imaging ; Hematology ; Hematopoietic Stem Cell Transplantation - adverse effects ; Hematopoietic stem cells ; Humans ; Internal Medicine ; Liver ; Liver - diagnostic imaging ; Male ; Medical sciences ; Medicine ; Medicine & Public Health ; Middle Aged ; Morbidity ; original-article ; Perfusion ; Physiological aspects ; Public Health ; Radiation ; Risk Assessment ; Sound waves ; Spleen ; Spleen - diagnostic imaging ; Stem cell research ; Stem cell transplantation ; Stem Cells ; Stiffness ; Transfusions. Complications. Transfusion reactions. Cell and gene therapy ; Transplantation ; Ultrasonic imaging ; Ultrasonics in medicine ; Ultrasonography, Doppler ; Ultrasound</subject><ispartof>Bone marrow transplantation (Basingstoke), 2014-06, Vol.49 (6), p.806-811</ispartof><rights>Macmillan Publishers Limited 2014</rights><rights>2015 INIST-CNRS</rights><rights>COPYRIGHT 2014 Nature Publishing Group</rights><rights>Copyright Nature Publishing Group Jun 2014</rights><rights>Macmillan Publishers Limited 2014.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c543t-996898adc8200fb56b4fcf3e805b00261c5cff387172c4d0c878ee6ed27f9de03</citedby><cites>FETCH-LOGICAL-c543t-996898adc8200fb56b4fcf3e805b00261c5cff387172c4d0c878ee6ed27f9de03</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1038/bmt.2014.61$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1038/bmt.2014.61$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>314,780,784,27922,27923,41486,42555,51317</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=28538834$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/24710567$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Karlas, T</creatorcontrib><creatorcontrib>Weber, J</creatorcontrib><creatorcontrib>Nehring, C</creatorcontrib><creatorcontrib>Kronenberger, R</creatorcontrib><creatorcontrib>Tenckhoff, H</creatorcontrib><creatorcontrib>Mössner, J</creatorcontrib><creatorcontrib>Niederwieser, D</creatorcontrib><creatorcontrib>Tröltzsch, M</creatorcontrib><creatorcontrib>Lange, T</creatorcontrib><creatorcontrib>Keim, V</creatorcontrib><title>Value of liver elastography and abdominal ultrasound for detection of complications of allogeneic hemopoietic SCT</title><title>Bone marrow transplantation (Basingstoke)</title><addtitle>Bone Marrow Transplant</addtitle><addtitle>Bone Marrow Transplant</addtitle><description>Hepatic complications contribute to morbidity and mortality after allogeneic hemopoietic SCT. Liver Doppler ultrasound and elastography represent promising methods for pretransplant risk assessment and early detection of complications. Ultrasound (liver and spleen size, liver perfusion) and elastography (transient elastography (TE); right liver lobe acoustic radiation force impulse imaging (r-ARFI); left liver lobe ARFI (l-ARFI)) were prospectively evaluated in patients with indications for allo-SCT. Measurements were performed before and repeatedly after SCT. Results were compared with the incidence of life-threatening complications and death during the first 150 days after SCT. Of 59 included patients, 16 suffered from major complications and 9 of them died within the follow-up period. At baseline, liver and spleen size, liver perfusion, TE and r-ARFI did not differ significantly between patients with and without severe complications. In contrast, l-ARFI was significantly elevated in patients who later developed severe complications (1.58±0.30 m/s vs 1.37±0.27 m/s,
P
=0.030). After SCT, l-ARFI values remained elevated and TE showed increasing liver stiffness in patients with complications. The value of conventional liver ultrasound for prediction of severe SCT complications is limited. Increased values for TE and l-ARFI are associated with severe SCT complications and demand further evaluation.</description><subject>631/250/1904</subject><subject>692/699/1503/1607</subject><subject>692/700/1421</subject><subject>692/700/565/2194</subject><subject>Abdomen - diagnostic imaging</subject><subject>Adult</subject><subject>Aged</subject><subject>Allografts</subject><subject>Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy</subject><subject>Biological and medical sciences</subject><subject>Bone marrow</subject><subject>Bone marrow, stem cells transplantation. Graft versus host reaction</subject><subject>Cell Biology</subject><subject>Cohort Studies</subject><subject>Complications</subject><subject>Doppler effect</subject><subject>Elasticity Imaging Techniques - methods</subject><subject>Evaluation</subject><subject>Female</subject><subject>Graft vs Host Disease - diagnostic imaging</subject><subject>Hematology</subject><subject>Hematopoietic Stem Cell Transplantation - adverse effects</subject><subject>Hematopoietic stem cells</subject><subject>Humans</subject><subject>Internal Medicine</subject><subject>Liver</subject><subject>Liver - diagnostic imaging</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Medicine</subject><subject>Medicine & Public Health</subject><subject>Middle Aged</subject><subject>Morbidity</subject><subject>original-article</subject><subject>Perfusion</subject><subject>Physiological aspects</subject><subject>Public Health</subject><subject>Radiation</subject><subject>Risk Assessment</subject><subject>Sound waves</subject><subject>Spleen</subject><subject>Spleen - diagnostic imaging</subject><subject>Stem cell research</subject><subject>Stem cell transplantation</subject><subject>Stem Cells</subject><subject>Stiffness</subject><subject>Transfusions. Complications. Transfusion reactions. Cell and gene therapy</subject><subject>Transplantation</subject><subject>Ultrasonic imaging</subject><subject>Ultrasonics in medicine</subject><subject>Ultrasonography, Doppler</subject><subject>Ultrasound</subject><issn>0268-3369</issn><issn>1476-5365</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2014</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><recordid>eNqNkk1v1DAQhiMEotvCiTuKhFohQRZ_xzlWK76kShwoXC3HGe-6cuLUTpD673HYhbaoQsgH2-NnZjSv36J4gdEaIyrftf20JgiztcCPihVmtag4FfxxsUJEyIpS0RwVxyldoQwxxJ8WR4TVGHFRr4rr79rPUAZbevcDYglepylsox53N6UeulK3XejdoH05-ynqFOYctCGWHUxgJheGJdmEfvTO6OWeloD2PmxhAGfKHfRhDA6mfP66uXxWPLHaJ3h-2E-Kbx_eX24-VRdfPn7enF9UhjM6VU0jZCN1ZyRByLZctMwaS0Ei3qI8GDbcWEtljWtiWIeMrCWAgI7UtukA0ZPi9b7uGMP1DGlSvUsGvNcDhDkpzDlrOOGS_QdKScMxqUlGX_2FXoU5ZnmSIoIRwrFomn9RuRZuapnHuKW22oNygw1ZYLO0Vue0JlJSymim1g9QeXXQOxMGsC7H7yWc3UnYgfbTLgU___qb--CbPWhiSCmCVWN0vY43CiO1WEtla6nFWkrgTL88zDS3PXR_2N9eysDpAdDJaG-jHoxLt5zkNDde1H6751J-GrYQ74jzQN-fGtziKw</recordid><startdate>20140601</startdate><enddate>20140601</enddate><creator>Karlas, T</creator><creator>Weber, J</creator><creator>Nehring, C</creator><creator>Kronenberger, R</creator><creator>Tenckhoff, H</creator><creator>Mössner, J</creator><creator>Niederwieser, D</creator><creator>Tröltzsch, M</creator><creator>Lange, T</creator><creator>Keim, V</creator><general>Nature Publishing Group UK</general><general>Nature Publishing Group</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7QO</scope><scope>7QP</scope><scope>7T5</scope><scope>7U9</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8FD</scope><scope>8FE</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BHPHI</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FR3</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>H94</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>LK8</scope><scope>M0S</scope><scope>M1P</scope><scope>M7N</scope><scope>M7P</scope><scope>P64</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope></search><sort><creationdate>20140601</creationdate><title>Value of liver elastography and abdominal ultrasound for detection of complications of allogeneic hemopoietic SCT</title><author>Karlas, T ; Weber, J ; Nehring, C ; Kronenberger, R ; Tenckhoff, H ; Mössner, J ; Niederwieser, D ; Tröltzsch, M ; Lange, T ; Keim, V</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c543t-996898adc8200fb56b4fcf3e805b00261c5cff387172c4d0c878ee6ed27f9de03</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2014</creationdate><topic>631/250/1904</topic><topic>692/699/1503/1607</topic><topic>692/700/1421</topic><topic>692/700/565/2194</topic><topic>Abdomen - diagnostic imaging</topic><topic>Adult</topic><topic>Aged</topic><topic>Allografts</topic><topic>Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy</topic><topic>Biological and medical sciences</topic><topic>Bone marrow</topic><topic>Bone marrow, stem cells transplantation. Graft versus host reaction</topic><topic>Cell Biology</topic><topic>Cohort Studies</topic><topic>Complications</topic><topic>Doppler effect</topic><topic>Elasticity Imaging Techniques - methods</topic><topic>Evaluation</topic><topic>Female</topic><topic>Graft vs Host Disease - diagnostic imaging</topic><topic>Hematology</topic><topic>Hematopoietic Stem Cell Transplantation - adverse effects</topic><topic>Hematopoietic stem cells</topic><topic>Humans</topic><topic>Internal Medicine</topic><topic>Liver</topic><topic>Liver - diagnostic imaging</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Medicine</topic><topic>Medicine & Public Health</topic><topic>Middle Aged</topic><topic>Morbidity</topic><topic>original-article</topic><topic>Perfusion</topic><topic>Physiological aspects</topic><topic>Public Health</topic><topic>Radiation</topic><topic>Risk Assessment</topic><topic>Sound waves</topic><topic>Spleen</topic><topic>Spleen - diagnostic imaging</topic><topic>Stem cell research</topic><topic>Stem cell transplantation</topic><topic>Stem Cells</topic><topic>Stiffness</topic><topic>Transfusions. Complications. Transfusion reactions. Cell and gene therapy</topic><topic>Transplantation</topic><topic>Ultrasonic imaging</topic><topic>Ultrasonics in medicine</topic><topic>Ultrasonography, Doppler</topic><topic>Ultrasound</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Karlas, T</creatorcontrib><creatorcontrib>Weber, J</creatorcontrib><creatorcontrib>Nehring, C</creatorcontrib><creatorcontrib>Kronenberger, R</creatorcontrib><creatorcontrib>Tenckhoff, H</creatorcontrib><creatorcontrib>Mössner, J</creatorcontrib><creatorcontrib>Niederwieser, D</creatorcontrib><creatorcontrib>Tröltzsch, M</creatorcontrib><creatorcontrib>Lange, T</creatorcontrib><creatorcontrib>Keim, V</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Biotechnology Research Abstracts</collection><collection>Calcium & Calcified Tissue Abstracts</collection><collection>Immunology Abstracts</collection><collection>Virology and AIDS Abstracts</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Technology Research Database</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>ProQuest Central</collection><collection>Natural Science Collection (ProQuest)</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Engineering Research Database</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>ProQuest Biological Science Collection</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Algology Mycology and Protozoology Abstracts (Microbiology C)</collection><collection>Biological Science Database</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><jtitle>Bone marrow transplantation (Basingstoke)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Karlas, T</au><au>Weber, J</au><au>Nehring, C</au><au>Kronenberger, R</au><au>Tenckhoff, H</au><au>Mössner, J</au><au>Niederwieser, D</au><au>Tröltzsch, M</au><au>Lange, T</au><au>Keim, V</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Value of liver elastography and abdominal ultrasound for detection of complications of allogeneic hemopoietic SCT</atitle><jtitle>Bone marrow transplantation (Basingstoke)</jtitle><stitle>Bone Marrow Transplant</stitle><addtitle>Bone Marrow Transplant</addtitle><date>2014-06-01</date><risdate>2014</risdate><volume>49</volume><issue>6</issue><spage>806</spage><epage>811</epage><pages>806-811</pages><issn>0268-3369</issn><eissn>1476-5365</eissn><coden>BMTRE9</coden><abstract>Hepatic complications contribute to morbidity and mortality after allogeneic hemopoietic SCT. Liver Doppler ultrasound and elastography represent promising methods for pretransplant risk assessment and early detection of complications. Ultrasound (liver and spleen size, liver perfusion) and elastography (transient elastography (TE); right liver lobe acoustic radiation force impulse imaging (r-ARFI); left liver lobe ARFI (l-ARFI)) were prospectively evaluated in patients with indications for allo-SCT. Measurements were performed before and repeatedly after SCT. Results were compared with the incidence of life-threatening complications and death during the first 150 days after SCT. Of 59 included patients, 16 suffered from major complications and 9 of them died within the follow-up period. At baseline, liver and spleen size, liver perfusion, TE and r-ARFI did not differ significantly between patients with and without severe complications. In contrast, l-ARFI was significantly elevated in patients who later developed severe complications (1.58±0.30 m/s vs 1.37±0.27 m/s,
P
=0.030). After SCT, l-ARFI values remained elevated and TE showed increasing liver stiffness in patients with complications. The value of conventional liver ultrasound for prediction of severe SCT complications is limited. Increased values for TE and l-ARFI are associated with severe SCT complications and demand further evaluation.</abstract><cop>London</cop><pub>Nature Publishing Group UK</pub><pmid>24710567</pmid><doi>10.1038/bmt.2014.61</doi><tpages>6</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0268-3369 |
| ispartof | Bone marrow transplantation (Basingstoke), 2014-06, Vol.49 (6), p.806-811 |
| issn | 0268-3369 1476-5365 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_1554952584 |
| source | MEDLINE; Nature; EZB-FREE-00999 freely available EZB journals; SpringerLink Journals - AutoHoldings |
| subjects | 631/250/1904 692/699/1503/1607 692/700/1421 692/700/565/2194 Abdomen - diagnostic imaging Adult Aged Allografts Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy Biological and medical sciences Bone marrow Bone marrow, stem cells transplantation. Graft versus host reaction Cell Biology Cohort Studies Complications Doppler effect Elasticity Imaging Techniques - methods Evaluation Female Graft vs Host Disease - diagnostic imaging Hematology Hematopoietic Stem Cell Transplantation - adverse effects Hematopoietic stem cells Humans Internal Medicine Liver Liver - diagnostic imaging Male Medical sciences Medicine Medicine & Public Health Middle Aged Morbidity original-article Perfusion Physiological aspects Public Health Radiation Risk Assessment Sound waves Spleen Spleen - diagnostic imaging Stem cell research Stem cell transplantation Stem Cells Stiffness Transfusions. Complications. Transfusion reactions. Cell and gene therapy Transplantation Ultrasonic imaging Ultrasonics in medicine Ultrasonography, Doppler Ultrasound |
| title | Value of liver elastography and abdominal ultrasound for detection of complications of allogeneic hemopoietic SCT |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-09T11%3A21%3A20IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-gale_proqu&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Value%20of%20liver%20elastography%20and%20abdominal%20ultrasound%20for%20detection%20of%20complications%20of%20allogeneic%20hemopoietic%20SCT&rft.jtitle=Bone%20marrow%20transplantation%20(Basingstoke)&rft.au=Karlas,%20T&rft.date=2014-06-01&rft.volume=49&rft.issue=6&rft.spage=806&rft.epage=811&rft.pages=806-811&rft.issn=0268-3369&rft.eissn=1476-5365&rft.coden=BMTRE9&rft_id=info:doi/10.1038/bmt.2014.61&rft_dat=%3Cgale_proqu%3EA372883343%3C/gale_proqu%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1531978805&rft_id=info:pmid/24710567&rft_galeid=A372883343&rfr_iscdi=true |