Molecular and cellular regulation of hypothalamic melanocortin neurons controlling food intake and energy metabolism

The brain receives and integrates environmental and metabolic information, transforms these signals into adequate neuronal circuit activities, and generates physiological behaviors to promote energy homeostasis. The responsible neuronal circuitries show lifetime plasticity and guaranty metabolic hea...

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Veröffentlicht in:	Molecular psychiatry 2014-07, Vol.19 (7), p.752-761
Hauptverfasser:	Koch, M, Horvath, T L
Format:	Artikel
Sprache:	eng
Schlagworte:	631/378/1488 631/443/319/333/1465 692/699/317 692/699/476 Agouti-Related Protein - physiology Animals Behavioral Sciences Bioenergetics Biological and medical sciences Biological Psychology Brain Brain research Eating - physiology Energy balance Energy consumption Energy metabolism Energy Metabolism - physiology expert-review Food Food habits Food intake Glial cells Homeostasis Humans Hypothalamus Hypothalamus - physiology Hypothalamus - physiopathology Medical sciences Medicine Medicine & Public Health Melanocortin Melanocortins - physiology Mental disorders Mental Disorders - physiopathology Metabolic disorders Metabolism Models, Neurological Neurobiology Neuroglia - physiology Neuronal-glial interactions Neurons Neurons - physiology Neuropeptide Y - physiology Neurophysiology Neurosciences Obesity Organelles - physiology Pharmacotherapy Physical activity Physiological aspects Physiology Pro-Opiomelanocortin - physiology Psychiatry Psychological aspects Psychology. Psychoanalysis. Psychiatry Psychopathology. Psychiatry Spinal cord
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