Noncoding RNA and its associated proteins as regulatory elements of the immune system

Non-coding RNA accounts for a large proportion of the mammalian genome. In this Focus Review, Martin Turner and colleagues explore how these RNA species regulate gene transcription in the immune system. The rapid changes in gene expression that accompany developmental transitions, stress responses a...

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Veröffentlicht in:	Nature immunology 2014-06, Vol.15 (6), p.484-491
Hauptverfasser:	Turner, Martin, Galloway, Alison, Vigorito, Elena
Format:	Artikel
Sprache:	eng
Schlagworte:	631/250/2502 Animals Biomedicine Gene Expression - immunology Genetic aspects Genetic regulation Hematopoiesis - genetics Humans Immune system Immune System - immunology Immunity, Cellular - genetics Immunity, Cellular - immunology Immunology Infectious Diseases Life cycles Lymphocyte Activation - genetics Lymphocyte Activation - immunology Mice Pathogens Physiological aspects Proteins review-article RNA RNA Processing, Post-Transcriptional - genetics RNA Processing, Post-Transcriptional - immunology RNA, Long Noncoding - genetics RNA, Small Untranslated - genetics RNA-Binding Proteins - genetics Signal Transduction - genetics Transcription, Genetic
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