Genetic linkage analysis identifies Pas1 as the common locus modulating lung tumorigenesis and acute inflammatory response in mice

Selective breeding for the acute inflammatory response (AIR) generated two mouse lines characterized by maximum (AIRmax) and minimum (AIRmin) responses, explained by the additive effect of alleles differentially fixed in quantitative trait loci (QTLs). These mice also differ in their susceptibility...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Genes and immunity 2013-12, Vol.14 (8), p.512-517
Hauptverfasser:	Galvan, A, Cabrera, W, Vorraro, F, Jensen, J R, Borrego, A, Starobinas, N, Ribeiro, O G, Franco, M De, Knott, S, Dragani, T A, Manenti, G, Ibañez, O C M
Format:	Artikel
Sprache:	eng
Schlagworte:	631/208/207 631/250/256 631/67/1612 631/67/68 Adenoma Alleles Animals Biomedical and Life Sciences Biomedicine Breeding Cancer Research Carcinogenesis Carcinogenesis - genetics Chemokines Chromosome 6 Chromosome Mapping Chromosomes - genetics Chronic obstructive pulmonary disease Cytokines Gene Expression Gene polymorphism Genes Genetic analysis Genetic aspects Genetic Linkage Genomes Human Genetics Identification and classification Immunology Inflammation Inflammation - genetics Leukocytes Linkage (Genetics) Linkage analysis Lung cancer Lung Neoplasms - genetics Mice original-article Phenotypes Polymorphism Polymorphism, Single Nucleotide Quantitative Trait Loci Single-nucleotide polymorphism Tumorigenesis Tumors
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!