Mutations in the FPIV motif of Newcastle disease virus matrix protein attenuate virus replication and reduce virus budding

The FPIV-like late domains identified in the matrix (M) proteins of parainfluenza virus 5 and mumps virus have been demonstrated to be critical for virus budding. In this study, we found that the same FPIV sequence motif is present in the N-terminus of the Newcastle disease virus (NDV) M protein. Mu...

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Veröffentlicht in:Archives of virology 2014-07, Vol.159 (7), p.1813-1819
Hauptverfasser: Duan, Zhiqiang, Hu, Zenglei, Zhu, Jie, Xu, Haixu, Chen, Jian, Liu, Huimou, Hu, Shunlin, Liu, Xiufan
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Sprache:eng
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