ADP-ribosylation of brain synaptosomal proteins correlates with adenylate cyclase activation

ADP-ribosylation of the adenylate cyclase G F regulatory subunit by cholera toxin is a major tool for the study of this enzyme. Investigation of the brain enzyme has been hampered up to now by the failure to demonstrate cholera toxin-dependent ADP-ribosylation of membrane-bound proteins. Synaptosome...

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Veröffentlicht in:	Biochemical and biophysical research communications 1982-11, Vol.109 (2), p.297-304
Hauptverfasser:	Berthillier, Gisèle, d'Alayer, Jacque, Monneron, Ariane
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenosine Diphosphate Ribose - metabolism Adenosine Triphosphate - metabolism adenylate cyclase Adenylyl Cyclases - metabolism ADP-ribosylation Animals brain Brain - metabolism Cholera Toxin - pharmacology Egtazic Acid - pharmacology Enzyme Activation Guanosine Triphosphate - metabolism Membrane Proteins - metabolism Molecular Weight NAD - metabolism Nerve Tissue Proteins - metabolism Nucleoside Diphosphate Sugars - metabolism Rats synaptosomes Synaptosomes - metabolism
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