Unusual reaction behavior of gem-difluorocyclopropane derivatives: stereoselective synthesis of β-monofluoroallylic alcohols, ethers, esters, and amide

On treating gem-difluorocyclopropylstannanes, derived from the radical hydrostannation of gem-difluorocyclopropenes, with 1.5 equiv of MeLi in THF at -78 °C for 5 min, followed by quenching the reaction with various agents, such as H2O, alcohols, carboxylic acids, and tosylamide, the corresponding β...

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Veröffentlicht in:	Organic letters 2014-08, Vol.16 (16), p.4170-4173
Hauptverfasser:	Nihei, Takashi, Hoshino, Tomoko, Konno, Tsutomu
Format:	Artikel
Sprache:	eng
Schlagworte:	Alcohols - chemical synthesis Alcohols - chemistry Amides - chemistry Carboxylic Acids Cyclopropanes - chemistry Esters Ethers - chemistry Hydrocarbons, Fluorinated - chemistry Molecular Structure Stereoisomerism
Online-Zugang:	Volltext
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