Cross-talk between free and bound spermatozoa to modulate initial sperm:egg ratios at the site of fertilization in the mammalian oviduct
This essay proposes that highly localized communication between free and bound spermatozoa in the caudal portion of the oviduct acts to regulate the numbers detaching from the epithelium and progressing to the site of fertilization close to the time of ovulation. Low initial sperm:egg ratios are ess...
Gespeichert in:
| Veröffentlicht in: | Theriogenology 2014-08, Vol.82 (3), p.367-372 |
|---|---|
| Hauptverfasser: | , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 372 |
|---|---|
| container_issue | 3 |
| container_start_page | 367 |
| container_title | Theriogenology |
| container_volume | 82 |
| creator | Hunter, R.H.F. Gadea, J. |
| description | This essay proposes that highly localized communication between free and bound spermatozoa in the caudal portion of the oviduct acts to regulate the numbers detaching from the epithelium and progressing to the site of fertilization close to the time of ovulation. Low initial sperm:egg ratios are essential for monospermic fertilization. Liberation of surface macromolecules and metabolic prompting from activated spermatozoa, together with altered patterns of sperm movement and dynamic differences in intracellular Ca2+ ion status between neighboring sperm cells, would influence the progressive release of spermatozoa from the reservoir in the oviduct isthmus. Different intensities of preovulatory epithelial binding, reflecting a range of states in the sperm surface membranes and associated proteins, would provide a further explanation for a chronologically staggered periovulatory detachment of spermatozoa. Intimate sperm–sperm interactions within the confines of the oviduct isthmus offer a sensitive means of fine-tuning the vanguard of competent male gametes reaching the isthmo-ampullary junction. |
| doi_str_mv | 10.1016/j.theriogenology.2014.04.015 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_1553313333</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>S0093691X14001940</els_id><sourcerecordid>1553313333</sourcerecordid><originalsourceid>FETCH-LOGICAL-c456t-d7e0de38787194cd37e12491ebae159a434b37afdf6b15fe8d1d73987e4a44713</originalsourceid><addsrcrecordid>eNqNUcFu1DAQtRCILgu_gHzgwCWLZ-3ECeKCVhSQKnGhUm_WJJ4sXpJ4sZ1W7Rfw2ThsqdQbo9H48N6b8cxj7A2IDQio3h026QcF5_c0-cHvbzdbAWojckL5hK2g1k0htxKespUQjSyqBq7O2IsYD0IIWVXwnJ1tVSNFJaoV-70LPsYi4fCTt5RuiCbeByKOk-Wtn3ONRwojJn_nkSfPR2_nARNxN7nkcDjh72m_5wGT85Fj4vmLPLpM8j3vKSQ3uLsFnLLqLzjiOOLgcOL-2tm5Sy_Zsx6HSK_u3zW7PP_0ffeluPj2-evu40XRqbJKhdUkLMla1xoa1VmpCfI2QC0SlA0qqVqpsbd91ULZU23BatnUmhQqpUGu2dtT32Pwv2aKyYwudjQMOJGfo4GylBLkEmv24UTtlhsF6s0xuBHDrQFhFi_MwTz2wixeGJETyix_fT9pbkeyD-J_x8-E8xOB8r7XjoKJnaOpI-sCdclY7_5v0h-Lv6b9</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1553313333</pqid></control><display><type>article</type><title>Cross-talk between free and bound spermatozoa to modulate initial sperm:egg ratios at the site of fertilization in the mammalian oviduct</title><source>MEDLINE</source><source>Access via ScienceDirect (Elsevier)</source><creator>Hunter, R.H.F. ; Gadea, J.</creator><creatorcontrib>Hunter, R.H.F. ; Gadea, J.</creatorcontrib><description>This essay proposes that highly localized communication between free and bound spermatozoa in the caudal portion of the oviduct acts to regulate the numbers detaching from the epithelium and progressing to the site of fertilization close to the time of ovulation. Low initial sperm:egg ratios are essential for monospermic fertilization. Liberation of surface macromolecules and metabolic prompting from activated spermatozoa, together with altered patterns of sperm movement and dynamic differences in intracellular Ca2+ ion status between neighboring sperm cells, would influence the progressive release of spermatozoa from the reservoir in the oviduct isthmus. Different intensities of preovulatory epithelial binding, reflecting a range of states in the sperm surface membranes and associated proteins, would provide a further explanation for a chronologically staggered periovulatory detachment of spermatozoa. Intimate sperm–sperm interactions within the confines of the oviduct isthmus offer a sensitive means of fine-tuning the vanguard of competent male gametes reaching the isthmo-ampullary junction.</description><identifier>ISSN: 0093-691X</identifier><identifier>EISSN: 1879-3231</identifier><identifier>DOI: 10.1016/j.theriogenology.2014.04.015</identifier><identifier>PMID: 24930606</identifier><language>eng</language><publisher>United States: Elsevier Inc</publisher><subject>Animals ; Capacitation ; Chemotaxis ; Female ; Fertilization - physiology ; Male ; Mammals - physiology ; Oviducts - physiology ; Progesterone ; Sperm competition ; Sperm conversations ; Sperm Motility ; Sperm-Ovum Interactions ; Spermatozoa - physiology</subject><ispartof>Theriogenology, 2014-08, Vol.82 (3), p.367-372</ispartof><rights>2014 Elsevier Inc.</rights><rights>Copyright © 2014 Elsevier Inc. All rights reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c456t-d7e0de38787194cd37e12491ebae159a434b37afdf6b15fe8d1d73987e4a44713</citedby><cites>FETCH-LOGICAL-c456t-d7e0de38787194cd37e12491ebae159a434b37afdf6b15fe8d1d73987e4a44713</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/j.theriogenology.2014.04.015$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,780,784,3550,27924,27925,45995</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/24930606$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Hunter, R.H.F.</creatorcontrib><creatorcontrib>Gadea, J.</creatorcontrib><title>Cross-talk between free and bound spermatozoa to modulate initial sperm:egg ratios at the site of fertilization in the mammalian oviduct</title><title>Theriogenology</title><addtitle>Theriogenology</addtitle><description>This essay proposes that highly localized communication between free and bound spermatozoa in the caudal portion of the oviduct acts to regulate the numbers detaching from the epithelium and progressing to the site of fertilization close to the time of ovulation. Low initial sperm:egg ratios are essential for monospermic fertilization. Liberation of surface macromolecules and metabolic prompting from activated spermatozoa, together with altered patterns of sperm movement and dynamic differences in intracellular Ca2+ ion status between neighboring sperm cells, would influence the progressive release of spermatozoa from the reservoir in the oviduct isthmus. Different intensities of preovulatory epithelial binding, reflecting a range of states in the sperm surface membranes and associated proteins, would provide a further explanation for a chronologically staggered periovulatory detachment of spermatozoa. Intimate sperm–sperm interactions within the confines of the oviduct isthmus offer a sensitive means of fine-tuning the vanguard of competent male gametes reaching the isthmo-ampullary junction.</description><subject>Animals</subject><subject>Capacitation</subject><subject>Chemotaxis</subject><subject>Female</subject><subject>Fertilization - physiology</subject><subject>Male</subject><subject>Mammals - physiology</subject><subject>Oviducts - physiology</subject><subject>Progesterone</subject><subject>Sperm competition</subject><subject>Sperm conversations</subject><subject>Sperm Motility</subject><subject>Sperm-Ovum Interactions</subject><subject>Spermatozoa - physiology</subject><issn>0093-691X</issn><issn>1879-3231</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2014</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqNUcFu1DAQtRCILgu_gHzgwCWLZ-3ECeKCVhSQKnGhUm_WJJ4sXpJ4sZ1W7Rfw2ThsqdQbo9H48N6b8cxj7A2IDQio3h026QcF5_c0-cHvbzdbAWojckL5hK2g1k0htxKespUQjSyqBq7O2IsYD0IIWVXwnJ1tVSNFJaoV-70LPsYi4fCTt5RuiCbeByKOk-Wtn3ONRwojJn_nkSfPR2_nARNxN7nkcDjh72m_5wGT85Fj4vmLPLpM8j3vKSQ3uLsFnLLqLzjiOOLgcOL-2tm5Sy_Zsx6HSK_u3zW7PP_0ffeluPj2-evu40XRqbJKhdUkLMla1xoa1VmpCfI2QC0SlA0qqVqpsbd91ULZU23BatnUmhQqpUGu2dtT32Pwv2aKyYwudjQMOJGfo4GylBLkEmv24UTtlhsF6s0xuBHDrQFhFi_MwTz2wixeGJETyix_fT9pbkeyD-J_x8-E8xOB8r7XjoKJnaOpI-sCdclY7_5v0h-Lv6b9</recordid><startdate>20140801</startdate><enddate>20140801</enddate><creator>Hunter, R.H.F.</creator><creator>Gadea, J.</creator><general>Elsevier Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20140801</creationdate><title>Cross-talk between free and bound spermatozoa to modulate initial sperm:egg ratios at the site of fertilization in the mammalian oviduct</title><author>Hunter, R.H.F. ; Gadea, J.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c456t-d7e0de38787194cd37e12491ebae159a434b37afdf6b15fe8d1d73987e4a44713</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2014</creationdate><topic>Animals</topic><topic>Capacitation</topic><topic>Chemotaxis</topic><topic>Female</topic><topic>Fertilization - physiology</topic><topic>Male</topic><topic>Mammals - physiology</topic><topic>Oviducts - physiology</topic><topic>Progesterone</topic><topic>Sperm competition</topic><topic>Sperm conversations</topic><topic>Sperm Motility</topic><topic>Sperm-Ovum Interactions</topic><topic>Spermatozoa - physiology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Hunter, R.H.F.</creatorcontrib><creatorcontrib>Gadea, J.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Theriogenology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Hunter, R.H.F.</au><au>Gadea, J.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Cross-talk between free and bound spermatozoa to modulate initial sperm:egg ratios at the site of fertilization in the mammalian oviduct</atitle><jtitle>Theriogenology</jtitle><addtitle>Theriogenology</addtitle><date>2014-08-01</date><risdate>2014</risdate><volume>82</volume><issue>3</issue><spage>367</spage><epage>372</epage><pages>367-372</pages><issn>0093-691X</issn><eissn>1879-3231</eissn><abstract>This essay proposes that highly localized communication between free and bound spermatozoa in the caudal portion of the oviduct acts to regulate the numbers detaching from the epithelium and progressing to the site of fertilization close to the time of ovulation. Low initial sperm:egg ratios are essential for monospermic fertilization. Liberation of surface macromolecules and metabolic prompting from activated spermatozoa, together with altered patterns of sperm movement and dynamic differences in intracellular Ca2+ ion status between neighboring sperm cells, would influence the progressive release of spermatozoa from the reservoir in the oviduct isthmus. Different intensities of preovulatory epithelial binding, reflecting a range of states in the sperm surface membranes and associated proteins, would provide a further explanation for a chronologically staggered periovulatory detachment of spermatozoa. Intimate sperm–sperm interactions within the confines of the oviduct isthmus offer a sensitive means of fine-tuning the vanguard of competent male gametes reaching the isthmo-ampullary junction.</abstract><cop>United States</cop><pub>Elsevier Inc</pub><pmid>24930606</pmid><doi>10.1016/j.theriogenology.2014.04.015</doi><tpages>6</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0093-691X |
| ispartof | Theriogenology, 2014-08, Vol.82 (3), p.367-372 |
| issn | 0093-691X 1879-3231 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_1553313333 |
| source | MEDLINE; Access via ScienceDirect (Elsevier) |
| subjects | Animals Capacitation Chemotaxis Female Fertilization - physiology Male Mammals - physiology Oviducts - physiology Progesterone Sperm competition Sperm conversations Sperm Motility Sperm-Ovum Interactions Spermatozoa - physiology |
| title | Cross-talk between free and bound spermatozoa to modulate initial sperm:egg ratios at the site of fertilization in the mammalian oviduct |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-26T02%3A43%3A02IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Cross-talk%20between%20free%20and%20bound%20spermatozoa%20to%20modulate%20initial%20sperm:egg%20ratios%20at%20the%20site%20of%20fertilization%20in%20the%20mammalian%20oviduct&rft.jtitle=Theriogenology&rft.au=Hunter,%20R.H.F.&rft.date=2014-08-01&rft.volume=82&rft.issue=3&rft.spage=367&rft.epage=372&rft.pages=367-372&rft.issn=0093-691X&rft.eissn=1879-3231&rft_id=info:doi/10.1016/j.theriogenology.2014.04.015&rft_dat=%3Cproquest_cross%3E1553313333%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1553313333&rft_id=info:pmid/24930606&rft_els_id=S0093691X14001940&rfr_iscdi=true |