Liquid chromatographic determination of caffeine in biologic fluids

A high-performance liquid chromatographic procedure was developed for the determination of caffeine in various biologic fluids and coffee. A reversed-phase column and UV detection at 254 nm were used to obtain a sensitivity of 0.1 μg/ml caffeine in serum and saliva using a sample volume of 0.1 ml. C...

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Veröffentlicht in:Journal of Chromatography A 1982-01, Vol.229 (2), p.387-395
Hauptverfasser: Haughey, David B., Greenberg, Richard, Schaal, Stephen F., Lima, John J.
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Sprache:eng
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