Recent developments in gold(i) coordination chemistry: luminescence properties and bioimaging opportunities

The fascinating biological activity of gold coordination compounds has led to the development of a wide range of complexes. The precise biological action of such species is often poorly understood and the ability to map gold distribution in cellular environments is key. This article discusses the re...

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Veröffentlicht in:	Chemical communications (Cambridge, England) England), 2014-09, Vol.5 (72), p.1343-1354
Hauptverfasser:	Langdon-Jones, Emily E, Pope, Simon J. A
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Auranofin - chemistry Auranofin - toxicity Biological activity Cell Line, Tumor Cell Proliferation - drug effects Coordination Complexes - chemistry Coordination Complexes - toxicity Coordination compounds Crystallography, X-Ray Gold Gold - chemistry Heterocyclic Compounds - chemistry Humans Luminescence Medical imaging Mice Microscopy, Confocal Molecular Conformation Optical properties Spectrometry, Fluorescence Utilities
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Zusammenfassung:	The fascinating biological activity of gold coordination compounds has led to the development of a wide range of complexes. The precise biological action of such species is often poorly understood and the ability to map gold distribution in cellular environments is key. This article discusses the recent progress in luminescent Au( i ) complexes whilst considering their utility in bioimaging and therapeutics. This article discusses the recent progress in luminescent Au( i ) complexes whilst considering their utility in bioimaging and therapeutics.
ISSN:	1359-7345 1364-548X
DOI:	10.1039/c4cc03259d