Recent advances in synthetic analogues of lantibiotics: What can we learn from these?

The lantibiotics are a family of antibacterial cyclic peptides distinguished by one or more thioether linkages between amino acid side chains, and by unique modes of action. Recent developments in the chemical synthesis, mutagenesis and mutasynthesis of these peptides are providing insights into the...

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Veröffentlicht in:	Bioorganic chemistry 2014-08, Vol.55, p.39-50
1. Verfasser:	Tabor, Alethea B.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Anti-Bacterial Agents - pharmacology Antibacterial Bacteria - drug effects Bacterial Infections - drug therapy Bacteriocins - chemistry Bacteriocins - pharmacology Humans Lantibiotic Peptide Peptides, Cyclic - chemistry Peptides, Cyclic - pharmacology
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