MicroRNA-23a is involved in tumor necrosis factor-α induced apoptosis in mesenchymal stem cells and myocardial infarction

Cell therapy has emerged as an attractive therapeutic modality to treat myocardial infarction (MI) via repairing damaged myocardium, and mesenchymal stem cells (MSCs) are an appealing therapeutic approach for cardiac regeneration. However, the clinical application of MSC-based therapy is restricted...

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Veröffentlicht in:	Experimental and molecular pathology 2014-08, Vol.97 (1), p.23-30
Hauptverfasser:	Mao, Jianqiang, Lv, Zhiqian, Zhuang, Yu
Format:	Artikel
Sprache:	eng
Schlagworte:	3' Untranslated Regions Animals Apoptosis Apoptosis - drug effects Apoptosis - genetics Caspase Caspase 7 - genetics Caspase 7 - metabolism Cells, Cultured Disease Models, Animal Dose-Response Relationship, Drug Gene Expression Regulation Heart Ventricles - pathology HEK293 Cells Humans Male Mesenchymal Stem Cell Transplantation Mesenchymal stem cells Mesenchymal Stromal Cells - drug effects Mesenchymal Stromal Cells - pathology MicroRNA MicroRNAs Myocardial infarction Myocardial Infarction - genetics Myocardial Infarction - pathology Rats Rats, Sprague-Dawley Tumor Necrosis Factor-alpha - metabolism Tumor Necrosis Factor-alpha - pharmacology
Online-Zugang:	Volltext
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