Impact of Intraoperative Topical Hydroxypropyl Methylcellulose 2% Versus Sodium Hyaluronate 1.2% on Corneal Reepithelialization After Intentional Epithelial Debridement During Vitrectomy
PURPOSE:The aim of this study was to assess the impact of the intraoperative use of topical hydroxypropyl methylcellulose (HPMC) 2% versus sodium hyaluronate 1.2% on corneal reepithelialization time and final corneal status after intentional epithelial debridement during vitrectomy for proliferative...
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| Veröffentlicht in: | Cornea 2014-09, Vol.33 (9), p.942-945 |
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| creator | Tosi, Gian Marco Marigliani, Davide Bacci, Tommaso Balestrazzi, Angelo Martone, Gianluca Polito, Maria Sole |
| description | PURPOSE:The aim of this study was to assess the impact of the intraoperative use of topical hydroxypropyl methylcellulose (HPMC) 2% versus sodium hyaluronate 1.2% on corneal reepithelialization time and final corneal status after intentional epithelial debridement during vitrectomy for proliferative vitreoretinopathy.
METHODS:Forty eyes of 40 patients were included in the study, divided into 2 groups of 20 eyes. HPMC 2% and sodium hyaluronate 1.2% were used as corneal protectors in the first and second group, respectively. Patientsʼ charts were reviewed to determine any differences between the HPMC 2% and sodium hyaluronate 1.2% groups in relation to the preoperative, intraoperative, and postoperative factors that could impact postoperative corneal reepithelialization. Postoperative reepithelialization time and final corneal status were recorded.
RESULTS:No significant between-group differences in preoperative, intraoperative, and postoperative factors were found. Reepithelialization time was significantly shorter in the sodium hyaluronate 1.2% group than in the HPMC 2% group, although reepithelialization was eventually achieved in every patient in both groups. Corneal sequelae were significantly more frequent in the HPMC 2% group than in the sodium hyaluronate 1.2% group.
CONCLUSIONS:The choice of the ophthalmic viscosurgical device for intraoperative corneal protection may significantly influence the postoperative corneal status after complicated retinal detachment. |
| doi_str_mv | 10.1097/ICO.0000000000000201 |
| format | Article |
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METHODS:Forty eyes of 40 patients were included in the study, divided into 2 groups of 20 eyes. HPMC 2% and sodium hyaluronate 1.2% were used as corneal protectors in the first and second group, respectively. Patientsʼ charts were reviewed to determine any differences between the HPMC 2% and sodium hyaluronate 1.2% groups in relation to the preoperative, intraoperative, and postoperative factors that could impact postoperative corneal reepithelialization. Postoperative reepithelialization time and final corneal status were recorded.
RESULTS:No significant between-group differences in preoperative, intraoperative, and postoperative factors were found. Reepithelialization time was significantly shorter in the sodium hyaluronate 1.2% group than in the HPMC 2% group, although reepithelialization was eventually achieved in every patient in both groups. Corneal sequelae were significantly more frequent in the HPMC 2% group than in the sodium hyaluronate 1.2% group.
CONCLUSIONS:The choice of the ophthalmic viscosurgical device for intraoperative corneal protection may significantly influence the postoperative corneal status after complicated retinal detachment.</description><identifier>ISSN: 0277-3740</identifier><identifier>EISSN: 1536-4798</identifier><identifier>DOI: 10.1097/ICO.0000000000000201</identifier><identifier>PMID: 25055149</identifier><language>eng</language><publisher>United States: by Lippincott Williams & Wilkins</publisher><subject>Administration, Topical ; Aged ; Debridement ; Epithelium, Corneal - physiology ; Female ; Humans ; Hyaluronic Acid - therapeutic use ; Hypromellose Derivatives - therapeutic use ; Intraoperative Care ; Male ; Middle Aged ; Ophthalmic Solutions ; Re-Epithelialization - physiology ; Viscosupplements - therapeutic use ; Vitrectomy ; Wound Healing - drug effects</subject><ispartof>Cornea, 2014-09, Vol.33 (9), p.942-945</ispartof><rights>2014 by Lippincott Williams & Wilkins.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c3891-dc7d7d5fc7bb0bd2c4e777775ced6001c1ff69b8ce695e381616b124687d07d23</citedby><cites>FETCH-LOGICAL-c3891-dc7d7d5fc7bb0bd2c4e777775ced6001c1ff69b8ce695e381616b124687d07d23</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/25055149$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Tosi, Gian Marco</creatorcontrib><creatorcontrib>Marigliani, Davide</creatorcontrib><creatorcontrib>Bacci, Tommaso</creatorcontrib><creatorcontrib>Balestrazzi, Angelo</creatorcontrib><creatorcontrib>Martone, Gianluca</creatorcontrib><creatorcontrib>Polito, Maria Sole</creatorcontrib><title>Impact of Intraoperative Topical Hydroxypropyl Methylcellulose 2% Versus Sodium Hyaluronate 1.2% on Corneal Reepithelialization After Intentional Epithelial Debridement During Vitrectomy</title><title>Cornea</title><addtitle>Cornea</addtitle><description>PURPOSE:The aim of this study was to assess the impact of the intraoperative use of topical hydroxypropyl methylcellulose (HPMC) 2% versus sodium hyaluronate 1.2% on corneal reepithelialization time and final corneal status after intentional epithelial debridement during vitrectomy for proliferative vitreoretinopathy.
METHODS:Forty eyes of 40 patients were included in the study, divided into 2 groups of 20 eyes. HPMC 2% and sodium hyaluronate 1.2% were used as corneal protectors in the first and second group, respectively. Patientsʼ charts were reviewed to determine any differences between the HPMC 2% and sodium hyaluronate 1.2% groups in relation to the preoperative, intraoperative, and postoperative factors that could impact postoperative corneal reepithelialization. Postoperative reepithelialization time and final corneal status were recorded.
RESULTS:No significant between-group differences in preoperative, intraoperative, and postoperative factors were found. Reepithelialization time was significantly shorter in the sodium hyaluronate 1.2% group than in the HPMC 2% group, although reepithelialization was eventually achieved in every patient in both groups. Corneal sequelae were significantly more frequent in the HPMC 2% group than in the sodium hyaluronate 1.2% group.
CONCLUSIONS:The choice of the ophthalmic viscosurgical device for intraoperative corneal protection may significantly influence the postoperative corneal status after complicated retinal detachment.</description><subject>Administration, Topical</subject><subject>Aged</subject><subject>Debridement</subject><subject>Epithelium, Corneal - physiology</subject><subject>Female</subject><subject>Humans</subject><subject>Hyaluronic Acid - therapeutic use</subject><subject>Hypromellose Derivatives - therapeutic use</subject><subject>Intraoperative Care</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Ophthalmic Solutions</subject><subject>Re-Epithelialization - physiology</subject><subject>Viscosupplements - therapeutic use</subject><subject>Vitrectomy</subject><subject>Wound Healing - drug effects</subject><issn>0277-3740</issn><issn>1536-4798</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2014</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kcFu1DAURS0EotPCHyDkDVI3GewktpNlNS10pFaVoHQbOfYLY3DiYDuU9NP4OhxNW1Us-jaWdc97V7oXoXeUrCmpxcft5mpNnk5O6Au0oqzgWSnq6iVakVyIrBAlOUCHIfxIjBA8f40OckYYo2W9Qn-3_ShVxK7D2yF66UbwMprfgK_daJS0-HzW3v2ZR-_G2eJLiLvZKrB2si4Azj_gG_BhCvir02bqEy7t5N0gI2C6TrIb8Mb5AdKpLwCjiTuwRlpzl2ySdtJF8Is3DMs_UWePDD6F1hsNfdLw6eTN8B3fmOhBRdfPb9CrTtoAb-_fI_Tt09n15jy7uPq83ZxcZKqoapppJbTQrFOibUmrc1WCWIYp0JwQqmjX8bqtFPCaQVFRTnlL85JXQhOh8-IIHe_vpgh-TRBi05uwJCAHcFNoKGN5weuyKhNa7lHlXQgeumb0ppd-bihpltaa1Frzf2tp7f29w9T2oB-XHmpKQLUHbp1NcYWfdroF3-xSqHH3_O1_zB-n8w</recordid><startdate>201409</startdate><enddate>201409</enddate><creator>Tosi, Gian Marco</creator><creator>Marigliani, Davide</creator><creator>Bacci, Tommaso</creator><creator>Balestrazzi, Angelo</creator><creator>Martone, Gianluca</creator><creator>Polito, Maria Sole</creator><general>by Lippincott Williams & Wilkins</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>201409</creationdate><title>Impact of Intraoperative Topical Hydroxypropyl Methylcellulose 2% Versus Sodium Hyaluronate 1.2% on Corneal Reepithelialization After Intentional Epithelial Debridement During Vitrectomy</title><author>Tosi, Gian Marco ; Marigliani, Davide ; Bacci, Tommaso ; Balestrazzi, Angelo ; Martone, Gianluca ; Polito, Maria Sole</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3891-dc7d7d5fc7bb0bd2c4e777775ced6001c1ff69b8ce695e381616b124687d07d23</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2014</creationdate><topic>Administration, Topical</topic><topic>Aged</topic><topic>Debridement</topic><topic>Epithelium, Corneal - physiology</topic><topic>Female</topic><topic>Humans</topic><topic>Hyaluronic Acid - therapeutic use</topic><topic>Hypromellose Derivatives - therapeutic use</topic><topic>Intraoperative Care</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Ophthalmic Solutions</topic><topic>Re-Epithelialization - physiology</topic><topic>Viscosupplements - therapeutic use</topic><topic>Vitrectomy</topic><topic>Wound Healing - drug effects</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Tosi, Gian Marco</creatorcontrib><creatorcontrib>Marigliani, Davide</creatorcontrib><creatorcontrib>Bacci, Tommaso</creatorcontrib><creatorcontrib>Balestrazzi, Angelo</creatorcontrib><creatorcontrib>Martone, Gianluca</creatorcontrib><creatorcontrib>Polito, Maria Sole</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Cornea</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Tosi, Gian Marco</au><au>Marigliani, Davide</au><au>Bacci, Tommaso</au><au>Balestrazzi, Angelo</au><au>Martone, Gianluca</au><au>Polito, Maria Sole</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Impact of Intraoperative Topical Hydroxypropyl Methylcellulose 2% Versus Sodium Hyaluronate 1.2% on Corneal Reepithelialization After Intentional Epithelial Debridement During Vitrectomy</atitle><jtitle>Cornea</jtitle><addtitle>Cornea</addtitle><date>2014-09</date><risdate>2014</risdate><volume>33</volume><issue>9</issue><spage>942</spage><epage>945</epage><pages>942-945</pages><issn>0277-3740</issn><eissn>1536-4798</eissn><abstract>PURPOSE:The aim of this study was to assess the impact of the intraoperative use of topical hydroxypropyl methylcellulose (HPMC) 2% versus sodium hyaluronate 1.2% on corneal reepithelialization time and final corneal status after intentional epithelial debridement during vitrectomy for proliferative vitreoretinopathy.
METHODS:Forty eyes of 40 patients were included in the study, divided into 2 groups of 20 eyes. HPMC 2% and sodium hyaluronate 1.2% were used as corneal protectors in the first and second group, respectively. Patientsʼ charts were reviewed to determine any differences between the HPMC 2% and sodium hyaluronate 1.2% groups in relation to the preoperative, intraoperative, and postoperative factors that could impact postoperative corneal reepithelialization. Postoperative reepithelialization time and final corneal status were recorded.
RESULTS:No significant between-group differences in preoperative, intraoperative, and postoperative factors were found. Reepithelialization time was significantly shorter in the sodium hyaluronate 1.2% group than in the HPMC 2% group, although reepithelialization was eventually achieved in every patient in both groups. Corneal sequelae were significantly more frequent in the HPMC 2% group than in the sodium hyaluronate 1.2% group.
CONCLUSIONS:The choice of the ophthalmic viscosurgical device for intraoperative corneal protection may significantly influence the postoperative corneal status after complicated retinal detachment.</abstract><cop>United States</cop><pub>by Lippincott Williams & Wilkins</pub><pmid>25055149</pmid><doi>10.1097/ICO.0000000000000201</doi><tpages>4</tpages></addata></record> |
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| subjects | Administration, Topical Aged Debridement Epithelium, Corneal - physiology Female Humans Hyaluronic Acid - therapeutic use Hypromellose Derivatives - therapeutic use Intraoperative Care Male Middle Aged Ophthalmic Solutions Re-Epithelialization - physiology Viscosupplements - therapeutic use Vitrectomy Wound Healing - drug effects |
| title | Impact of Intraoperative Topical Hydroxypropyl Methylcellulose 2% Versus Sodium Hyaluronate 1.2% on Corneal Reepithelialization After Intentional Epithelial Debridement During Vitrectomy |
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