Application of a sensitive and accurate LC-MS/MS method for determination of dryocrassin ABBA in rat plasma for a bioavailability study

ABSTRACT A sensitive and accurate liquid chromatography–tandem mass spectrometry method was developed and validated for the determination of dryocrassin ABBA, a potential active component isolated from Dryopteris crassirhizoma, in rat plasma. Chromatographic separation was achieved on a Zorbax SB‐C1...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Biomedical chromatography 2014-09, Vol.28 (9), p.1205-1211
Hauptverfasser:	Ding, Ya-Ming, Liu, Zhuo, Li, Fu-Qiang
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetates Animals Benzylidene Compounds - blood Benzylidene Compounds - chemistry Benzylidene Compounds - pharmacokinetics bioavailability Biological Availability Chromatography, Liquid - methods Cyclohexanones - blood Cyclohexanones - chemistry Cyclohexanones - pharmacokinetics Drug Stability dryocrassin ABBA LC-MS/MS Linear Models Male pharmacokinetics Rats Rats, Wistar Reproducibility of Results Sensitivity and Specificity Tandem Mass Spectrometry - methods
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!