A Role for H3K4 Monomethylation in Gene Repression and Partitioning of Chromatin Readers
Monomethylation of lysine 4 on histone H3 (H3K4me1) is a well-established feature of enhancers and promoters, although its function is unknown. Here, we uncover roles for H3K4me1 in diverse cell types. Remarkably, we find that MLL3/4 provokes monomethylation of promoter regions and the conditional r...
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Veröffentlicht in: | Molecular cell 2014-03, Vol.53 (6), p.979-992 |
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Sprache: | eng |
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