A new mutant transcript generated in Znf230 exon 2 knockout mice reveals a potential exon structure in the targeting vector sequence

Testis gene Znf230 may play a role in mammalian spermatogenesis according to previous reports. Deleting 5＇ important exons to block the formation of protein was a routine way in gene-knockout experiments. To investigate the physiological function of Znf230 gene, the mutant mice with disrupted exon 2...

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Veröffentlicht in:	Acta biochimica et biophysica Sinica 2013-02, Vol.45 (2), p.123-128
Hauptverfasser:	Liu, Yunqiang, Tao, Dachang, Ma, Sunkai, Kuang, Ying, Su, Dan, Zhang, Hao, Yang, Yuan, Ma, Yongxin, Zhang, Sizhong
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Base Sequence DNA-Binding Proteins - genetics Exons - genetics Gene Targeting - methods Genetic Vectors - genetics Male Mice Mice, Knockout Molecular Sequence Data Mutation - genetics Testis - metabolism Transcription Factors - genetics 基因敲除外显子2 子结构序列成绩打靶载体突变小鼠精子发生过程
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