Characterization of acetyl-CoA and propionyl-CoA carboxylases encoded by Leptospira interrogans serovar Lai： an initial biochemical study for leptospiral gluconeogenesis via anaplerotic CO2 assimilation

Leptospira interrogans is the causative agent of leptospirosis. The in vitro growth of L. interrogans requires CO2 and a partial 3-hydroxypropionate pathway involving two aeyl-CoA carboxylases was suggested by genomic analysis to assimilate CO2. Either set of the candidate genes heterologously co-ex...

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Veröffentlicht in:	Acta biochimica et biophysica Sinica 2012-08, Vol.44 (8), p.692-702
Hauptverfasser:	Peng, Nanqiu, Zhong, Yi, Zhang, Qing, Zheng, Mingyue, Zhao, Wei, Jiang, Hualiang, Yang, Chen, Guo, Xiaokui, Zhao, Guoping
Format:	Artikel
Sprache:	eng
Schlagworte:	CO2 Escherichia coli Leptospira interrogans 乙酰辅酶A 同化 基因组分析 底物特异性 表征 钩端螺旋体病 非变性聚丙烯酰胺凝胶电泳
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