P41Women's health study of Mycoplasma genitalium: a feasibility study

BackgroundThe role of Mycoplasma genitalium ( similar to 3% prevalence in women) in PID is unclear. An opportunity exists to study its natural history since there are no UK treatment guidelines. We conducted a feasibility study.ObjectivesIn women attending GUM clinics to determine: (1) recruitment a...

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Veröffentlicht in:Sexually transmitted infections 2012-06, Vol.88 (Suppl 1), p.A23-A23
Hauptverfasser: Dave, S, Kerry, S R, Oakeshott, P, McGregor, F, Cannon, E, Stephenson, J M
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container_end_page A23
container_issue Suppl 1
container_start_page A23
container_title Sexually transmitted infections
container_volume 88
creator Dave, S
Kerry, S R
Oakeshott, P
McGregor, F
Cannon, E
Stephenson, J M
description BackgroundThe role of Mycoplasma genitalium ( similar to 3% prevalence in women) in PID is unclear. An opportunity exists to study its natural history since there are no UK treatment guidelines. We conducted a feasibility study.ObjectivesIn women attending GUM clinics to determine: (1) recruitment and follow-up rates after 3 and 6months, (2) feasibility of obtaining NHS numbers, (3) facilitators and barriers to follow-up.MethodsWomen aged 16-24years recruited from two GUM clinics completed a questionnaire and provided two self-taken vaginal samples. One sample was tested for chlamydia. We are testing for M genitalium and conducting 3-month follow-up.ResultsRecruitment rate was 67% (199/296). Non-responders were similar in age to responders (20.6 SD 2.5 vs 20.7 SD 2.5years) but more likely to come from ethnic minority groups: 56% (37/66) vs 36% (71/195), p
doi_str_mv 10.1136/sextrans-2012-050601c.41
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An opportunity exists to study its natural history since there are no UK treatment guidelines. We conducted a feasibility study.ObjectivesIn women attending GUM clinics to determine: (1) recruitment and follow-up rates after 3 and 6months, (2) feasibility of obtaining NHS numbers, (3) facilitators and barriers to follow-up.MethodsWomen aged 16-24years recruited from two GUM clinics completed a questionnaire and provided two self-taken vaginal samples. One sample was tested for chlamydia. We are testing for M genitalium and conducting 3-month follow-up.ResultsRecruitment rate was 67% (199/296). Non-responders were similar in age to responders (20.6 SD 2.5 vs 20.7 SD 2.5years) but more likely to come from ethnic minority groups: 56% (37/66) vs 36% (71/195), p&lt;0.05. Among responders, mean sexual debut age was 16.3years (range 12-23 n=198); 59% (116/195) reported greater than or equal to 2 sexual partners and 17% (31/186) consistently used condoms in the preceding 12months. 8.2% (16/197) had chlamydia and 0.5% (1/197) gonorrhoea on testing. At recruitment 196 participants consented to NHS numbers being obtained and used to access medical records; 197 participants agreed to 3-month follow-up. We have been able to contact similar to 50% of participants for follow-up.DiscussionMost women consented to NHS number and medical record access. This is important for investigating long-term sequelae of STIs. Fewer women took part in follow-up than agreed at recruitment. It is important to understand the reasons for this.</description><identifier>ISSN: 1472-3263</identifier><identifier>DOI: 10.1136/sextrans-2012-050601c.41</identifier><language>eng</language><subject>Chlamydia ; Mycoplasma genitalium</subject><ispartof>Sexually transmitted infections, 2012-06, Vol.88 (Suppl 1), p.A23-A23</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27922,27923</link.rule.ids></links><search><creatorcontrib>Dave, S</creatorcontrib><creatorcontrib>Kerry, S R</creatorcontrib><creatorcontrib>Oakeshott, P</creatorcontrib><creatorcontrib>McGregor, F</creatorcontrib><creatorcontrib>Cannon, E</creatorcontrib><creatorcontrib>Stephenson, J M</creatorcontrib><title>P41Women's health study of Mycoplasma genitalium: a feasibility study</title><title>Sexually transmitted infections</title><description>BackgroundThe role of Mycoplasma genitalium ( similar to 3% prevalence in women) in PID is unclear. An opportunity exists to study its natural history since there are no UK treatment guidelines. We conducted a feasibility study.ObjectivesIn women attending GUM clinics to determine: (1) recruitment and follow-up rates after 3 and 6months, (2) feasibility of obtaining NHS numbers, (3) facilitators and barriers to follow-up.MethodsWomen aged 16-24years recruited from two GUM clinics completed a questionnaire and provided two self-taken vaginal samples. One sample was tested for chlamydia. We are testing for M genitalium and conducting 3-month follow-up.ResultsRecruitment rate was 67% (199/296). Non-responders were similar in age to responders (20.6 SD 2.5 vs 20.7 SD 2.5years) but more likely to come from ethnic minority groups: 56% (37/66) vs 36% (71/195), p&lt;0.05. Among responders, mean sexual debut age was 16.3years (range 12-23 n=198); 59% (116/195) reported greater than or equal to 2 sexual partners and 17% (31/186) consistently used condoms in the preceding 12months. 8.2% (16/197) had chlamydia and 0.5% (1/197) gonorrhoea on testing. At recruitment 196 participants consented to NHS numbers being obtained and used to access medical records; 197 participants agreed to 3-month follow-up. We have been able to contact similar to 50% of participants for follow-up.DiscussionMost women consented to NHS number and medical record access. This is important for investigating long-term sequelae of STIs. Fewer women took part in follow-up than agreed at recruitment. 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An opportunity exists to study its natural history since there are no UK treatment guidelines. We conducted a feasibility study.ObjectivesIn women attending GUM clinics to determine: (1) recruitment and follow-up rates after 3 and 6months, (2) feasibility of obtaining NHS numbers, (3) facilitators and barriers to follow-up.MethodsWomen aged 16-24years recruited from two GUM clinics completed a questionnaire and provided two self-taken vaginal samples. One sample was tested for chlamydia. We are testing for M genitalium and conducting 3-month follow-up.ResultsRecruitment rate was 67% (199/296). Non-responders were similar in age to responders (20.6 SD 2.5 vs 20.7 SD 2.5years) but more likely to come from ethnic minority groups: 56% (37/66) vs 36% (71/195), p&lt;0.05. 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subjects Chlamydia
Mycoplasma genitalium
title P41Women's health study of Mycoplasma genitalium: a feasibility study
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