Transcriptional regulation of IL-15 expression during hematopoiesis

Dendritic cells (DCs) are the most commonly studied source of the cytokine IL-15. Using an IL-15 reporter transgenic mouse, we have recently shown previously unappreciated differences in the levels of IL-15 expressed by subsets of conventional DCs (CD8⁺ and CD8⁻). In this study, we show that IL-15 p...

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Veröffentlicht in:	The Journal of immunology (1950) 2013-09, Vol.191 (6), p.3017-3024
Hauptverfasser:	Colpitts, Sara L, Stonier, Spencer W, Stoklasek, Thomas A, Root, Sierra H, Aguila, Hector Leonardo, Schluns, Kimberly S, Lefrançois, Leo
Format:	Artikel
Sprache:	eng
Schlagworte:	Adoptive Transfer Animals Cell Differentiation - immunology Cell Lineage Cell Separation Flow Cytometry Gene Expression Regulation - immunology Hematopoiesis - immunology Hematopoietic Stem Cells - cytology Hematopoietic Stem Cells - immunology Interleukin-15 - biosynthesis Interleukin-15 - immunology Mice Mice, Inbred C57BL Mice, Transgenic Myeloid Cells - immunology Transcription, Genetic
Online-Zugang:	Volltext
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