Staphylococcus aureus phenol-soluble modulin peptides modulate dendritic cell functions and increase in vitro priming of regulatory T cells

The major human pathogen Staphylococcus aureus has very efficient strategies to subvert the human immune system. Virulence of the emerging community-associated methicillin-resistant S. aureus depends on phenol-soluble modulin (PSM) peptide toxins, which are known to attract and lyse neutrophils. How...

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Veröffentlicht in:	The Journal of immunology (1950) 2013-04, Vol.190 (7), p.3417-3426
Hauptverfasser:	Schreiner, Jens, Kretschmer, Dorothee, Klenk, Juliane, Otto, Michael, Bühring, Hans-Jörg, Stevanovic, Stefan, Wang, Ji Ming, Beer-Hammer, Sandra, Peschel, Andreas, Autenrieth, Stella E
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Bacterial Toxins - chemistry Bacterial Toxins - immunology Chemotaxis - immunology Clathrin - metabolism Cytokines - metabolism Dendritic Cells - immunology Dendritic Cells - metabolism Endocytosis - immunology Female Lymphocyte Activation - immunology Mice Peptides - immunology Receptors, Formyl Peptide - metabolism Staphylococcus aureus Staphylococcus aureus - chemistry Staphylococcus aureus - immunology T-Lymphocytes, Regulatory - immunology Toll-Like Receptor 2 - metabolism
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