Activation of NK cell cytotoxicity by the natural compound 2,3-butanediol

2,3‐BTD activates NK cells cytotoxicity by NKG2D/NCRs pathways. The natural compound 2,3‐BTD has diverse physiological effects in a range of organisms, including acting as a detoxifying product of liver alcohol metabolism in humans and ameliorating endotoxin‐induced acute lung injury in rats. In thi...

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Veröffentlicht in:	Journal of leukocyte biology 2012-10, Vol.92 (4), p.807-814
Hauptverfasser:	Lai, Hsin‐Chih, Chang, Chih‐Jung, Yang, Chun‐Hung, Hsu, Ya‐Jing, Chen, Chang‐Chieh, Lin, Chuan‐Sheng, Tsai, Yu‐Huan, Huang, Tsung‐Teng, Ojcius, David M., Tsai, Ying‐Huang, Lu, Chia‐Chen
Format:	Artikel
Sprache:	eng
Schlagworte:	Butylene Glycols - pharmacology Cells, Cultured Cytotoxicity, Immunologic - drug effects Extracellular Signal-Regulated MAP Kinases - physiology Humans JNK Mitogen-Activated Protein Kinases - physiology Killer Cells, Natural - immunology Lymphocyte Activation - drug effects NCR NK Cell Lectin-Like Receptor Subfamily K - physiology NKG2D perforin Perforin - genetics resveratrol
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