An extracellular matrix-based mechanism of rapid neutrophil extracellular trap formation in response to Candida albicans

The armament of neutrophil-mediated host defense against pathogens includes the extrusion of a lattice of DNA and microbicidal enzymes known as neutrophil extracellular traps (NETs). The receptor/ligand interactions and intracellular signaling mechanisms responsible for elaborating NETs were determi...

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Veröffentlicht in:	The Journal of immunology (1950) 2013-04, Vol.190 (8), p.4136-4148
Hauptverfasser:	Byrd, Angel S, O'Brien, Xian M, Johnson, Courtney M, Lavigne, Liz M, Reichner, Jonathan S
Format:	Artikel
Sprache:	eng
Schlagworte:	beta-Glucans - metabolism Candida albicans Candida albicans - cytology Candida albicans - immunology Candida albicans - metabolism Cell Aggregation - immunology Extracellular Matrix - immunology Extracellular Matrix - metabolism Fibronectins - physiology Humans Macrophage-1 Antigen Neutrophils - cytology Neutrophils - immunology Neutrophils - metabolism Reactive Oxygen Species - immunology Reactive Oxygen Species - metabolism Respiratory Burst - immunology Time Factors
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