Effects of Dexamethasone on Mesenchymal Stromal Cell Chondrogenesis and Aggrecanase Activity

Objective: Dexamethasone (Dex) is a synthetic glucocorticoid that has pro-anabolic and anticatabolic effects in cartilage tissue engineering systems, though the mechanisms by which these effects are mediated are not well understood. We tested the hypothesis that the addition of Dex to chondrogenic m...

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Veröffentlicht in:Cartilage 2013-01, Vol.4 (1), p.63-74
Hauptverfasser: Florine, Emily M, Miller, Rachel E, Porter, Ryan M, Evans, Christopher H, Kurz, Bodo, Grodzinsky, Alan J
Format: Artikel
Sprache:eng
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