Potential contribution of a novel Tax epitope-specific CD4+ T cells to graft-versus-Tax effect in adult T cell leukemia patients after allogeneic hematopoietic stem cell transplantation

Allogeneic hematopoietic stem cell transplantation (allo-HSCT) is an effective treatment for adult T cell leukemia/lymphoma (ATL) caused by human T cell leukemia virus type 1 (HTLV-1). We previously reported that Tax-specific CD8(+) cytotoxic T lymphocyte (CTL) contributed to graft-versus-ATL effect...

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Veröffentlicht in:The Journal of immunology (1950) 2013-04, Vol.190 (8), p.4382-4392
Hauptverfasser: Tamai, Yotaro, Hasegawa, Atsuhiko, Takamori, Ayako, Sasada, Amane, Tanosaki, Ryuji, Choi, Ilseung, Utsunomiya, Atae, Maeda, Yasuhiro, Yamano, Yoshihisa, Eto, Tetsuya, Koh, Ki-Ryang, Nakamae, Hirohisa, Suehiro, Youko, Kato, Koji, Takemoto, Shigeki, Okamura, Jun, Uike, Naokuni, Kannagi, Mari
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Sprache:eng
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