Phenotypic and functional characterization of NK cells in human immune response against the dimorphic fungus Paracoccidioides brasiliensis

Besides their role in fighting viral infection and tumor resistance, recent studies have shown that NK cells also participate in the immune response against other infectious diseases. The aim of this study was to characterize the possible role of NK cells in the immune response against Paracoccidioi...

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Veröffentlicht in:	The Journal of immunology (1950) 2012-07, Vol.189 (2), p.935-945
Hauptverfasser:	Longhi, Larissa N A, da Silva, Rosiane M, Fornazim, Márcia C, Spago, Maria C, de Oliveira, Rômulo T D, Nowill, Alexandre E, Blotta, Maria H S L, Mamoni, Ronei L
Format:	Artikel
Sprache:	eng
Schlagworte:	Antifungal Agents - pharmacology Antigens, Differentiation, T-Lymphocyte - physiology Cell Movement - immunology Cells, Cultured Coculture Techniques Cytotoxicity, Immunologic - immunology Humans Immunophenotyping - methods Inflammation Mediators - physiology Interferon-gamma - biosynthesis K562 Cells Killer Cells, Natural - immunology Killer Cells, Natural - microbiology Killer Cells, Natural - pathology Lymphocyte Activation - immunology Paracoccidioides - immunology Paracoccidioides - pathogenicity Paracoccidioides brasiliensis Paracoccidioidomycosis - immunology Paracoccidioidomycosis - pathology Paracoccidioidomycosis - therapy Tumor Necrosis Factor-alpha - biosynthesis
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