Elvitegravir/Cobicistat/Emtricitabine/Tenofovir Disoproxil Fumarate Single Tablet for HIV-1 Infection Treatment

Objective: To review the clinical trials, pharmacologic characteristics, safety, and efficacy of the elvitegravir/cobicistat/emtricitabine/tenofovir single tablet formulation (Stribild). Data Sources: Literature searches were performed in MEDLINE (1948-September 2012) and PubMed (1966-September 2012...

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Veröffentlicht in:	The Annals of pharmacotherapy 2012-12, Vol.46 (12), p.1671-1677
Hauptverfasser:	Olin, Jacqueline L, Spooner, Linda M, Klibanov, Olga M
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenine - administration & dosage Adenine - adverse effects Adenine - analogs & derivatives Adenine - therapeutic use Anti-HIV Agents - administration & dosage Anti-HIV Agents - adverse effects Anti-HIV Agents - therapeutic use Carbamates - administration & dosage Carbamates - adverse effects Carbamates - therapeutic use Clinical Trials, Phase III as Topic Deoxycytidine - administration & dosage Deoxycytidine - adverse effects Deoxycytidine - therapeutic use Drug Combinations Elvitegravir, Cobicistat, Emtricitabine, Tenofovir Disoproxil Fumarate Drug Combination HIV Infections - drug therapy HIV Integrase Inhibitors - administration & dosage HIV Integrase Inhibitors - adverse effects HIV Integrase Inhibitors - therapeutic use Human immunodeficiency virus 1 Humans Organophosphonates - administration & dosage Organophosphonates - adverse effects Organophosphonates - therapeutic use Quinolones - administration & dosage Quinolones - adverse effects Quinolones - therapeutic use Tablets Thiazoles - administration & dosage Thiazoles - adverse effects Thiazoles - therapeutic use Viral Load - drug effects
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