Contemporary Midterm Echocardiographic Outcomes of Bentall Procedure and Aortic Valve Sparing Root Replacement

Background Valve sparing root replacement (VSRR) and aortic valve repair (AVr) is an attractive treatment option compared with composite valve and root replacement (Bentall procedure) for patients with aortic root dilatation with or without aortic valve disease. While aortic valve preservation reduc...

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Veröffentlicht in:The Annals of thoracic surgery 2014-08, Vol.98 (2), p.590-596
Hauptverfasser: Toeg, Hadi, MD, MS, Chan, Vincent, MD, MPH, Rao, Rajeev V., MD, Chan, Kwan-Leung, MD, Ruel, Marc, MD, MPH, Mesana, Thierry, MD, PhD, Boodhwani, Munir, MD, MMS
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container_issue 2
container_start_page 590
container_title The Annals of thoracic surgery
container_volume 98
creator Toeg, Hadi, MD, MS
Chan, Vincent, MD, MPH
Rao, Rajeev V., MD
Chan, Kwan-Leung, MD
Ruel, Marc, MD, MPH
Mesana, Thierry, MD, PhD
Boodhwani, Munir, MD, MMS
description Background Valve sparing root replacement (VSRR) and aortic valve repair (AVr) is an attractive treatment option compared with composite valve and root replacement (Bentall procedure) for patients with aortic root dilatation with or without aortic valve disease. While aortic valve preservation reduces the risk of valve-related complications, little is known about echocardiographic differences at follow-up between these 2 strategies. Methods Consecutive nonemergent patients undergoing VSRR and AVr (n = 68) were compared with contemporary historical controls undergoing the Bentall procedure for aortic root pathology with or without mixed aortic valve disease (insufficiency or stenosis) (n = 96). The VSRR was performed preferentially using the reimplantation technique. Bentall procedure utilized a mechanical valve in 65% of patients, a biologic prosthesis in 22%, and a homograft in 13%. Clinical and echocardiographic data were obtained at baseline and at follow-up (median = 30 months). Results The 2 cohorts were similar with respect to all preoperative characteristics with the exception of disease etiology. The Bentall group had a higher proportion of degenerative valve and root disease (47.8% vs 27.9%) and a lower proportion of bicuspid aortic valve disease (22.8% vs 51.5%) as compared with the VSRR group ( p  = 0.007). Postoperative echocardiographic outcomes were comparable between groups with the exception of higher peak (23.37 ± 11.80 vs 18.0 ± 12.04; p  =0.02) and mean (13.07 ± 7.53 vs 9.56 ± 6.49; p  = 0.01) transvalvular aortic gradients in the Bentall group. Persistence of left ventricular dysfunction (8.4% vs 6.1%; p  = 0.61), presence of greater than moderate aortic valve (AV) insufficiency (3% vs 4.6%; p  = 0.32), and left ventricular mass (213.24 ± 72.36 vs 207.38 ± 63.07, p  = 0.61) were comparable between the Bentall and VSRR group, respectively. Finally, survival ( p  = 0.21) and freedom from valve-related events ( p  = 0.74) were similar between groups. Conclusions Valve sparing root replacement with AV repair provides similar mid-term echocardiographic and clinical outcomes compared with the Bentall.
doi_str_mv 10.1016/j.athoracsur.2014.04.121
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While aortic valve preservation reduces the risk of valve-related complications, little is known about echocardiographic differences at follow-up between these 2 strategies. Methods Consecutive nonemergent patients undergoing VSRR and AVr (n = 68) were compared with contemporary historical controls undergoing the Bentall procedure for aortic root pathology with or without mixed aortic valve disease (insufficiency or stenosis) (n = 96). The VSRR was performed preferentially using the reimplantation technique. Bentall procedure utilized a mechanical valve in 65% of patients, a biologic prosthesis in 22%, and a homograft in 13%. Clinical and echocardiographic data were obtained at baseline and at follow-up (median = 30 months). Results The 2 cohorts were similar with respect to all preoperative characteristics with the exception of disease etiology. The Bentall group had a higher proportion of degenerative valve and root disease (47.8% vs 27.9%) and a lower proportion of bicuspid aortic valve disease (22.8% vs 51.5%) as compared with the VSRR group ( p  = 0.007). Postoperative echocardiographic outcomes were comparable between groups with the exception of higher peak (23.37 ± 11.80 vs 18.0 ± 12.04; p  =0.02) and mean (13.07 ± 7.53 vs 9.56 ± 6.49; p  = 0.01) transvalvular aortic gradients in the Bentall group. Persistence of left ventricular dysfunction (8.4% vs 6.1%; p  = 0.61), presence of greater than moderate aortic valve (AV) insufficiency (3% vs 4.6%; p  = 0.32), and left ventricular mass (213.24 ± 72.36 vs 207.38 ± 63.07, p  = 0.61) were comparable between the Bentall and VSRR group, respectively. Finally, survival ( p  = 0.21) and freedom from valve-related events ( p  = 0.74) were similar between groups. Conclusions Valve sparing root replacement with AV repair provides similar mid-term echocardiographic and clinical outcomes compared with the Bentall.</description><identifier>ISSN: 0003-4975</identifier><identifier>EISSN: 1552-6259</identifier><identifier>DOI: 10.1016/j.athoracsur.2014.04.121</identifier><identifier>PMID: 24968770</identifier><language>eng</language><publisher>Netherlands: Elsevier Inc</publisher><subject>Aortic Valve - diagnostic imaging ; Aortic Valve - surgery ; Bicuspid Aortic Valve Disease ; Cardiac Surgical Procedures - methods ; Cardiothoracic Surgery ; Female ; Heart Defects, Congenital - diagnostic imaging ; Heart Defects, Congenital - surgery ; Heart Valve Diseases - diagnostic imaging ; Heart Valve Diseases - surgery ; Heart Valve Prosthesis Implantation - methods ; Humans ; Male ; Middle Aged ; Surgery ; Time Factors ; Treatment Outcome ; Ultrasonography</subject><ispartof>The Annals of thoracic surgery, 2014-08, Vol.98 (2), p.590-596</ispartof><rights>The Society of Thoracic Surgeons</rights><rights>2014 The Society of Thoracic Surgeons</rights><rights>Copyright © 2014 The Society of Thoracic Surgeons. Published by Elsevier Inc. All rights reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c565t-b824a473c1b6937365ca8b1c32cdccba7974a87f962571f61221b6bea4fb07083</citedby><cites>FETCH-LOGICAL-c565t-b824a473c1b6937365ca8b1c32cdccba7974a87f962571f61221b6bea4fb07083</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27901,27902</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/24968770$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Toeg, Hadi, MD, MS</creatorcontrib><creatorcontrib>Chan, Vincent, MD, MPH</creatorcontrib><creatorcontrib>Rao, Rajeev V., MD</creatorcontrib><creatorcontrib>Chan, Kwan-Leung, MD</creatorcontrib><creatorcontrib>Ruel, Marc, MD, MPH</creatorcontrib><creatorcontrib>Mesana, Thierry, MD, PhD</creatorcontrib><creatorcontrib>Boodhwani, Munir, MD, MMS</creatorcontrib><title>Contemporary Midterm Echocardiographic Outcomes of Bentall Procedure and Aortic Valve Sparing Root Replacement</title><title>The Annals of thoracic surgery</title><addtitle>Ann Thorac Surg</addtitle><description>Background Valve sparing root replacement (VSRR) and aortic valve repair (AVr) is an attractive treatment option compared with composite valve and root replacement (Bentall procedure) for patients with aortic root dilatation with or without aortic valve disease. While aortic valve preservation reduces the risk of valve-related complications, little is known about echocardiographic differences at follow-up between these 2 strategies. Methods Consecutive nonemergent patients undergoing VSRR and AVr (n = 68) were compared with contemporary historical controls undergoing the Bentall procedure for aortic root pathology with or without mixed aortic valve disease (insufficiency or stenosis) (n = 96). The VSRR was performed preferentially using the reimplantation technique. Bentall procedure utilized a mechanical valve in 65% of patients, a biologic prosthesis in 22%, and a homograft in 13%. Clinical and echocardiographic data were obtained at baseline and at follow-up (median = 30 months). Results The 2 cohorts were similar with respect to all preoperative characteristics with the exception of disease etiology. The Bentall group had a higher proportion of degenerative valve and root disease (47.8% vs 27.9%) and a lower proportion of bicuspid aortic valve disease (22.8% vs 51.5%) as compared with the VSRR group ( p  = 0.007). Postoperative echocardiographic outcomes were comparable between groups with the exception of higher peak (23.37 ± 11.80 vs 18.0 ± 12.04; p  =0.02) and mean (13.07 ± 7.53 vs 9.56 ± 6.49; p  = 0.01) transvalvular aortic gradients in the Bentall group. Persistence of left ventricular dysfunction (8.4% vs 6.1%; p  = 0.61), presence of greater than moderate aortic valve (AV) insufficiency (3% vs 4.6%; p  = 0.32), and left ventricular mass (213.24 ± 72.36 vs 207.38 ± 63.07, p  = 0.61) were comparable between the Bentall and VSRR group, respectively. Finally, survival ( p  = 0.21) and freedom from valve-related events ( p  = 0.74) were similar between groups. Conclusions Valve sparing root replacement with AV repair provides similar mid-term echocardiographic and clinical outcomes compared with the Bentall.</description><subject>Aortic Valve - diagnostic imaging</subject><subject>Aortic Valve - surgery</subject><subject>Bicuspid Aortic Valve Disease</subject><subject>Cardiac Surgical Procedures - methods</subject><subject>Cardiothoracic Surgery</subject><subject>Female</subject><subject>Heart Defects, Congenital - diagnostic imaging</subject><subject>Heart Defects, Congenital - surgery</subject><subject>Heart Valve Diseases - diagnostic imaging</subject><subject>Heart Valve Diseases - surgery</subject><subject>Heart Valve Prosthesis Implantation - methods</subject><subject>Humans</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Surgery</subject><subject>Time Factors</subject><subject>Treatment Outcome</subject><subject>Ultrasonography</subject><issn>0003-4975</issn><issn>1552-6259</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2014</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqNkc1u1DAQxy0EokvhFZCPXBL8lTi5ILWr8iEVFbXA1XImk66XJA62U6lvw7PwZHi1BSROnKyRf_MfzW8IoZyVnPH69b60aeeDhbiGUjCuSqZKLvgjsuFVJYpaVO1jsmGMyUK1ujohz2Lc51Lk76fkRKi2brRmG-K3fk44LTks3NOPrk8YJnoBOw829M7fBrvsHNCrNYGfMFI_0HOckx1H-il4wH4NSO3c0zMfUga_2vEOf_64WWxw8y299j7Ra1xGCzjlvufkyWDHiC8e3lPy5e3F5-374vLq3Yft2WUBVV2lomuEskpL4F3dSi3rCmzTcZACeoDO6lYr2-ihzZtqPtRciEx2aNXQMc0aeUpeHXOX4L-vGJOZXAQcRzujX6PJHrgUjZB1RpsjCsHHGHAwS3BT1mE4MwfdZm_-6jYH3YYpk3Xn1pcPU9Zuwv5P42-_GTg_Aph3vXMYTASHc9bmAkIyvXf_M-XNPyEwutmBHb_hPca9X8OcXRpuojDM3BzOfrg6V4wzySv5Czb8rXA</recordid><startdate>20140801</startdate><enddate>20140801</enddate><creator>Toeg, Hadi, MD, MS</creator><creator>Chan, Vincent, MD, MPH</creator><creator>Rao, Rajeev V., MD</creator><creator>Chan, Kwan-Leung, MD</creator><creator>Ruel, Marc, MD, MPH</creator><creator>Mesana, Thierry, MD, PhD</creator><creator>Boodhwani, Munir, MD, MMS</creator><general>Elsevier Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20140801</creationdate><title>Contemporary Midterm Echocardiographic Outcomes of Bentall Procedure and Aortic Valve Sparing Root Replacement</title><author>Toeg, Hadi, MD, MS ; Chan, Vincent, MD, MPH ; Rao, Rajeev V., MD ; Chan, Kwan-Leung, MD ; Ruel, Marc, MD, MPH ; Mesana, Thierry, MD, PhD ; Boodhwani, Munir, MD, MMS</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c565t-b824a473c1b6937365ca8b1c32cdccba7974a87f962571f61221b6bea4fb07083</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2014</creationdate><topic>Aortic Valve - diagnostic imaging</topic><topic>Aortic Valve - surgery</topic><topic>Bicuspid Aortic Valve Disease</topic><topic>Cardiac Surgical Procedures - methods</topic><topic>Cardiothoracic Surgery</topic><topic>Female</topic><topic>Heart Defects, Congenital - diagnostic imaging</topic><topic>Heart Defects, Congenital - surgery</topic><topic>Heart Valve Diseases - diagnostic imaging</topic><topic>Heart Valve Diseases - surgery</topic><topic>Heart Valve Prosthesis Implantation - methods</topic><topic>Humans</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Surgery</topic><topic>Time Factors</topic><topic>Treatment Outcome</topic><topic>Ultrasonography</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Toeg, Hadi, MD, MS</creatorcontrib><creatorcontrib>Chan, Vincent, MD, MPH</creatorcontrib><creatorcontrib>Rao, Rajeev V., MD</creatorcontrib><creatorcontrib>Chan, Kwan-Leung, MD</creatorcontrib><creatorcontrib>Ruel, Marc, MD, MPH</creatorcontrib><creatorcontrib>Mesana, Thierry, MD, PhD</creatorcontrib><creatorcontrib>Boodhwani, Munir, MD, MMS</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>The Annals of thoracic surgery</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Toeg, Hadi, MD, MS</au><au>Chan, Vincent, MD, MPH</au><au>Rao, Rajeev V., MD</au><au>Chan, Kwan-Leung, MD</au><au>Ruel, Marc, MD, MPH</au><au>Mesana, Thierry, MD, PhD</au><au>Boodhwani, Munir, MD, MMS</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Contemporary Midterm Echocardiographic Outcomes of Bentall Procedure and Aortic Valve Sparing Root Replacement</atitle><jtitle>The Annals of thoracic surgery</jtitle><addtitle>Ann Thorac Surg</addtitle><date>2014-08-01</date><risdate>2014</risdate><volume>98</volume><issue>2</issue><spage>590</spage><epage>596</epage><pages>590-596</pages><issn>0003-4975</issn><eissn>1552-6259</eissn><abstract>Background Valve sparing root replacement (VSRR) and aortic valve repair (AVr) is an attractive treatment option compared with composite valve and root replacement (Bentall procedure) for patients with aortic root dilatation with or without aortic valve disease. While aortic valve preservation reduces the risk of valve-related complications, little is known about echocardiographic differences at follow-up between these 2 strategies. Methods Consecutive nonemergent patients undergoing VSRR and AVr (n = 68) were compared with contemporary historical controls undergoing the Bentall procedure for aortic root pathology with or without mixed aortic valve disease (insufficiency or stenosis) (n = 96). The VSRR was performed preferentially using the reimplantation technique. Bentall procedure utilized a mechanical valve in 65% of patients, a biologic prosthesis in 22%, and a homograft in 13%. Clinical and echocardiographic data were obtained at baseline and at follow-up (median = 30 months). Results The 2 cohorts were similar with respect to all preoperative characteristics with the exception of disease etiology. The Bentall group had a higher proportion of degenerative valve and root disease (47.8% vs 27.9%) and a lower proportion of bicuspid aortic valve disease (22.8% vs 51.5%) as compared with the VSRR group ( p  = 0.007). Postoperative echocardiographic outcomes were comparable between groups with the exception of higher peak (23.37 ± 11.80 vs 18.0 ± 12.04; p  =0.02) and mean (13.07 ± 7.53 vs 9.56 ± 6.49; p  = 0.01) transvalvular aortic gradients in the Bentall group. Persistence of left ventricular dysfunction (8.4% vs 6.1%; p  = 0.61), presence of greater than moderate aortic valve (AV) insufficiency (3% vs 4.6%; p  = 0.32), and left ventricular mass (213.24 ± 72.36 vs 207.38 ± 63.07, p  = 0.61) were comparable between the Bentall and VSRR group, respectively. Finally, survival ( p  = 0.21) and freedom from valve-related events ( p  = 0.74) were similar between groups. Conclusions Valve sparing root replacement with AV repair provides similar mid-term echocardiographic and clinical outcomes compared with the Bentall.</abstract><cop>Netherlands</cop><pub>Elsevier Inc</pub><pmid>24968770</pmid><doi>10.1016/j.athoracsur.2014.04.121</doi><tpages>7</tpages></addata></record>
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subjects Aortic Valve - diagnostic imaging
Aortic Valve - surgery
Bicuspid Aortic Valve Disease
Cardiac Surgical Procedures - methods
Cardiothoracic Surgery
Female
Heart Defects, Congenital - diagnostic imaging
Heart Defects, Congenital - surgery
Heart Valve Diseases - diagnostic imaging
Heart Valve Diseases - surgery
Heart Valve Prosthesis Implantation - methods
Humans
Male
Middle Aged
Surgery
Time Factors
Treatment Outcome
Ultrasonography
title Contemporary Midterm Echocardiographic Outcomes of Bentall Procedure and Aortic Valve Sparing Root Replacement
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