Activation of central α2 -adrenoceptors mediates salivary gland vasoconstriction

Abstract Objective Peripheral treatment with the cholinergic agonist pilocarpine increases salivary gland blood flow and induces intense salivation that is reduced by the central injection of moxonidine (α2 -adrenoceptors/imidazoline agonist). In the present study, we investigated the effects of the...

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Veröffentlicht in:	Archives of oral biology 2013-02, Vol.58 (2), p.167-173
Hauptverfasser:	Moreira, Thiago S, Takakura, Ana C, Menani, José V, Colombari, Eduardo
Format:	Artikel
Sprache:	eng
Schlagworte:	Advanced Basic Science Animals Blood flow and vascular resistance Dentistry Imidazoles - administration & dosage Imidazoles - pharmacology Injections Male Moxonidine Parasympathetic Pilocarpine Pilocarpine - administration & dosage Pilocarpine - pharmacology Rats Receptors, Adrenergic - drug effects Salivary gland Salivary Glands - drug effects Vascular Resistance - drug effects Vasoconstriction - drug effects Yohimbine - pharmacology α2-Adrenergic receptor
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