Monitoring cell culture media degradation using surface enhanced Raman scattering (SERS) spectroscopy

[Display omitted] •Rapid method for monitoring chemical changes in cell culture media.•Uses surface enhanced Raman scattering (SERS) spectroscopy to provide molecular information.•Very sensitive to changes in cysteine/cystine ratio. The quality of the cell culture media used in biopharmaceutical man...

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Veröffentlicht in:	Analytica chimica acta 2014-08, Vol.840, p.58-67
Hauptverfasser:	Calvet, Amandine, Ryder, Alan G.
Format:	Artikel
Sprache:	eng
Schlagworte:	Biotechnology Cell culture media Cell Culture Techniques - methods Chemometrics Culture Media - analysis Culture Media - metabolism Photo-degradation Photoelectron Spectroscopy - methods Raman spectroscopy Spectrum Analysis, Raman - methods Surface enhanced Raman scattering (SERS)
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