Radically Different Thioredoxin Domain Arrangement of ERp46, an Efficient Disulfide Bond Introducer of the Mammalian PDI Family

The mammalian endoplasmic reticulum (ER) contains a diverse oxidative protein folding network in which ERp46, a member of the protein disulfide isomerase (PDI) family, serves as an efficient disulfide bond introducer together with Peroxiredoxin-4 (Prx4). We revealed a radically different molecular a...

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Veröffentlicht in:Structure (London) 2014-03, Vol.22 (3), p.431-443
Hauptverfasser: Kojima, Rieko, Okumura, Masaki, Masui, Shoji, Kanemura, Shingo, Inoue, Michio, Saiki, Masatoshi, Yamaguchi, Hiroshi, Hikima, Takaaki, Suzuki, Mamoru, Akiyama, Shuji, Inaba, Kenji
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Sprache:eng
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