Adsorption and desorption of tyrosine kinase inhibitor erlotinib on gold nanoparticles

[Display omitted] •Adsorption and desorption of erlotinib were examined on gold nanoparticle surfaces.•Density functional theory calculations predicted plausible binding geometries.•Surface-enhanced Raman scattering was used to investigate the interfacial structures. We investigated interfacial beha...

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Veröffentlicht in:	Journal of colloid and interface science 2014-07, Vol.425 (425), p.96-101
Hauptverfasser:	Lam, Anh Thu Ngoc, Yoon, Jinha, Ganbold, Erdene-Ochir, Singh, Dheeraj K., Kim, Doseok, Cho, Kwang-Hwi, Son, Sang Jun, Choo, Jaebum, Lee, So Yeong, Kim, Sehun, Joo, Sang-Woo
Format:	Artikel
Sprache:	eng
Schlagworte:	Adsorption Binding Chemistry Colloidal state and disperse state Density functional theory Desorption Erlotinib Erlotinib Hydrochloride Exact sciences and technology General and physical chemistry Gold - chemistry Gold nanoparticles Inhibitors Interfacial structures Kinases Mathematical analysis Metal Nanoparticles Physical and chemical studies. Granulometry. Electrokinetic phenomena Protein Kinase Inhibitors - chemistry Protein-Tyrosine Kinases - antagonists & inhibitors Quinazolines - chemistry Raman scattering Raman spectroscopy Spectra Spectrum Analysis, Raman Surface chemistry Surface physical chemistry
Online-Zugang:	Volltext
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