Microbiota Modulate Tumoral Immune Surveillance in Lung through a γδT17 Immune Cell-Dependent Mechanism

Commensal bacteria are crucial to maintain immune homeostasis in mucosal tissues and disturbances in their ecology can affect disease susceptibility. Here, we report evidence that commensal bacteria shape the efficiency of immune surveillance in mucosal tissues. Antibiotic-treated (Abt) mice were mo...

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Veröffentlicht in:	Cancer research (Chicago, Ill.) Ill.), 2014-08, Vol.74 (15), p.4030-4041
Hauptverfasser:	Cheng, Min, Qian, Liting, Shen, Guodong, Bian, Geng, Xu, Tingjuan, Xu, Weiping, Shen, Gan, Hu, Shilian
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antineoplastic agents Biological and medical sciences Carcinoma, Lewis Lung - immunology Carcinoma, Lewis Lung - microbiology Female Immunologic Surveillance Interleukin-17 - immunology Medical sciences Melanoma, Experimental - immunology Melanoma, Experimental - microbiology Mice Mice, Inbred C57BL Microbiota - immunology Pharmacology. Drug treatments Receptors, Antigen, T-Cell, gamma-delta - immunology T-Lymphocytes - immunology Tumors
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