Lectin-decorated nanoparticles enhance binding to the inflamed tissue in experimental colitis

A major limitation in the drug treatment of inflammatory bowel disease is the inability to deliver the drug selectively towards the inflamed tissues. Nanotechnology-based drug delivery systems have led to an amelioration of the therapeutic selectivity but still the majority of the entrapped drug is...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Journal of controlled release 2014-08, Vol.188, p.9-17
Hauptverfasser:	Moulari, Brice, Béduneau, Arnaud, Pellequer, Yann, Lamprecht, Alf
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Binding Sites Colitis - drug therapy Colitis - metabolism Colitis - pathology Drug Carriers - chemistry Drug Carriers - metabolism Drug Delivery Systems Glucocorticoids - administration & dosage Glucocorticoids - therapeutic use Intestine, Large - drug effects Intestine, Large - metabolism Intestine, Large - pathology Male Mice Nanoparticles - chemistry Nanoparticles - metabolism Peanut Agglutinin - chemistry Peanut Agglutinin - metabolism Wheat Germ Agglutinins - chemistry Wheat Germ Agglutinins - metabolism
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!