Pancreatic Preproglucagon cDNA Contains Two Glucagon-Related Coding Sequences Arranged in Tandem

We have constructed and cloned in bacteria recombinant plasmids containing DNA complementary to the mRNA encoding a pancreatic preproglucagon (Mr14,500), a product of cell-free translation of angler fish islet mRNAs shown previously by immunoprecipitation analyses to be a precursor of glucagon. cDNA...

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Veröffentlicht in:	Proceedings of the National Academy of Sciences - PNAS 1982, Vol.79 (2), p.345-349
Hauptverfasser:	Lund, P. Kay, Goodman, Richard H., Dee, Phillip C., Habener, Joel F.
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Amino acids Animals Base Sequence Complementary DNA DNA - genetics Fish Fishers Fishes Gin Glucagon - genetics Hormones Islets of Langerhans - physiology Lophius piscatorius Messenger RNA Nucleotide sequences Nucleotides Plasmids Protein Precursors - genetics RNA, Messenger - genetics
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