Ankle Brachial Index Intensifies the Diagnostic Accuracy of Epicardial Fat Thickness for the Prediction of Coronary Artery Disease Complexity
Objectives Epicardial fat thickness (EFT) and Ankle brachial index (ABI) are associated with coronary artery disease (CAD). The SYNTAX score (SS) reflects the complexity of CAD. We aimed to evaluate the relation of EFT and ABI with CAD complexity. Methods We enrolled 197 patients undergoing coronary...
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| Veröffentlicht in: | Heart, lung & circulation lung & circulation, 2014-08, Vol.23 (8), p.764-771 |
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| creator | Aykan, Ahmet Çağrı, MD Gül, İlker, MD Gökdeniz, Tayyar, MD Hatem, Engin, MD Arslan, Ahmet Oğuz, MD Kalaycıoğlu, Ezgi, MD Turan, Turhan, MD Belen, Erdal, MD Çetin, Mustafa, MD |
| description | Objectives Epicardial fat thickness (EFT) and Ankle brachial index (ABI) are associated with coronary artery disease (CAD). The SYNTAX score (SS) reflects the complexity of CAD. We aimed to evaluate the relation of EFT and ABI with CAD complexity. Methods We enrolled 197 patients undergoing coronary angiography. In all patients, ABI and EFT were determined. SS was calculated. The relationship between EFT, ABI and SS was analysed. Results ABI and EFT were significantly correlated with SS (r = -0.525, p < 0.001, and r = 0.650, p < 0.001, respectively) and found to be independent predictors of SS. ABI22 with a sensitivity of 45.28% and a specificity of %82.64 (AUC = 0.689, %95 CI = 0.619-0.763, p |
| doi_str_mv | 10.1016/j.hlc.2014.03.007 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_1549636684</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>S144395061400122X</els_id><sourcerecordid>1549636684</sourcerecordid><originalsourceid>FETCH-LOGICAL-c544t-47dd71bba3c869ebefa05d2f6db15bb554262adcbb4a359ef0eaf751bbc371763</originalsourceid><addsrcrecordid>eNp9Uk2LFDEUbERx19Uf4EVy9NK9-er0NIIwzn64sKDgCt5COnlxMtOTjEladn6E_9n0zurBg5e88KgqeFVVVa8Jbggm4nzTrEfdUEx4g1mDcfekOiWc85ouevr04c_qvsXipHqR0gZj0nHWP69OKO8w52JxWv1a-u0I6ENUeu3UiG68gfvyZvDJWQcJ5TWgC6e--5Cy02ip9VTABxQsutw7raKZeVcqo7u101sPKSEb4gPvcwTjdHbBz_BViMGreEDLmKGMC5dAJSj73X6Ee5cPL6tnVo0JXj3Os-rr1eXd6mN9--n6ZrW8rXXLea55Z0xHhkExvRA9DGAVbg21wgykHYa25VRQZfQwcMXaHiwGZbu2MDTrSCfYWfX2qLuP4ccEKcudSxrGUXkIU5Kk5b1gQix4gZIjVMeQUgQr99HtyhWSYDmnIDeypCDnFCRmsqRQOG8e5adhB-Yv44_tBfDuCIBy5E8HUSbtwOviVgSdpQnuv_Lv_2Hr0fkSxbiFA6RNmKIv7kkiE5VYfplrMLeA8NIASr-x31OEr3o</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1549636684</pqid></control><display><type>article</type><title>Ankle Brachial Index Intensifies the Diagnostic Accuracy of Epicardial Fat Thickness for the Prediction of Coronary Artery Disease Complexity</title><source>MEDLINE</source><source>Elsevier ScienceDirect Journals Complete</source><creator>Aykan, Ahmet Çağrı, MD ; Gül, İlker, MD ; Gökdeniz, Tayyar, MD ; Hatem, Engin, MD ; Arslan, Ahmet Oğuz, MD ; Kalaycıoğlu, Ezgi, MD ; Turan, Turhan, MD ; Belen, Erdal, MD ; Çetin, Mustafa, MD</creator><creatorcontrib>Aykan, Ahmet Çağrı, MD ; Gül, İlker, MD ; Gökdeniz, Tayyar, MD ; Hatem, Engin, MD ; Arslan, Ahmet Oğuz, MD ; Kalaycıoğlu, Ezgi, MD ; Turan, Turhan, MD ; Belen, Erdal, MD ; Çetin, Mustafa, MD</creatorcontrib><description>Objectives Epicardial fat thickness (EFT) and Ankle brachial index (ABI) are associated with coronary artery disease (CAD). The SYNTAX score (SS) reflects the complexity of CAD. We aimed to evaluate the relation of EFT and ABI with CAD complexity. Methods We enrolled 197 patients undergoing coronary angiography. In all patients, ABI and EFT were determined. SS was calculated. The relationship between EFT, ABI and SS was analysed. Results ABI and EFT were significantly correlated with SS (r = -0.525, p < 0.001, and r = 0.650, p < 0.001, respectively) and found to be independent predictors of SS. ABI<0.9 mm identified patients with SS>22 with a sensitivity of 45.28% and a specificity of %82.64 (AUC = 0.689, %95 CI = 0.619-0.763, p<0.001). The optimal cutoff value for EFT was 5 mm, yielding a sensitivity of 81.1% and a specificity of 90.3% (AUC = 0.859, 95% CI 0.802–0.904). In order to identify which parameters were the most accurate, we compared both AUC of ROC curves and there was no difference (p = 0.170). Conclusion EFT and ABI enables the noninvasive prediction of CAD severity in patients with suspected CAD and combining ABI to EFT was additive for the prediction of coronary artery disease complexity.</description><identifier>ISSN: 1443-9506</identifier><identifier>EISSN: 1444-2892</identifier><identifier>DOI: 10.1016/j.hlc.2014.03.007</identifier><identifier>PMID: 24704468</identifier><language>eng</language><publisher>Australia: Elsevier B.V</publisher><subject>Adipose Tissue - diagnostic imaging ; Adipose Tissue - pathology ; Aged ; Angiography ; Ankle Brachial Index ; Cardiovascular ; Coronary ; Coronary Angiography ; Coronary Artery Disease - diagnosis ; Epicardial fat thickness ; Female ; Humans ; Male ; Middle Aged ; Pericardium - diagnostic imaging ; Pericardium - pathology ; Peripheral artery disease ; Prospective Studies ; Severity of Illness Index ; SYNTAX</subject><ispartof>Heart, lung & circulation, 2014-08, Vol.23 (8), p.764-771</ispartof><rights>Australian and New Zealand Society of Cardiac and Thoracic Surgeons (ANZSCTS) and the Cardiac Society of Australia and New Zealand (CSANZ)</rights><rights>2014 Australian and New Zealand Society of Cardiac and Thoracic Surgeons (ANZSCTS) and the Cardiac Society of Australia and New Zealand (CSANZ)</rights><rights>Copyright © 2014 Australian and New Zealand Society of Cardiac and Thoracic Surgeons (ANZSCTS) and the Cardiac Society of Australia and New Zealand (CSANZ). Published by Elsevier B.V. All rights reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c544t-47dd71bba3c869ebefa05d2f6db15bb554262adcbb4a359ef0eaf751bbc371763</citedby><cites>FETCH-LOGICAL-c544t-47dd71bba3c869ebefa05d2f6db15bb554262adcbb4a359ef0eaf751bbc371763</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/S144395061400122X$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,776,780,3537,27901,27902,65306</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/24704468$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Aykan, Ahmet Çağrı, MD</creatorcontrib><creatorcontrib>Gül, İlker, MD</creatorcontrib><creatorcontrib>Gökdeniz, Tayyar, MD</creatorcontrib><creatorcontrib>Hatem, Engin, MD</creatorcontrib><creatorcontrib>Arslan, Ahmet Oğuz, MD</creatorcontrib><creatorcontrib>Kalaycıoğlu, Ezgi, MD</creatorcontrib><creatorcontrib>Turan, Turhan, MD</creatorcontrib><creatorcontrib>Belen, Erdal, MD</creatorcontrib><creatorcontrib>Çetin, Mustafa, MD</creatorcontrib><title>Ankle Brachial Index Intensifies the Diagnostic Accuracy of Epicardial Fat Thickness for the Prediction of Coronary Artery Disease Complexity</title><title>Heart, lung & circulation</title><addtitle>Heart Lung Circ</addtitle><description>Objectives Epicardial fat thickness (EFT) and Ankle brachial index (ABI) are associated with coronary artery disease (CAD). The SYNTAX score (SS) reflects the complexity of CAD. We aimed to evaluate the relation of EFT and ABI with CAD complexity. Methods We enrolled 197 patients undergoing coronary angiography. In all patients, ABI and EFT were determined. SS was calculated. The relationship between EFT, ABI and SS was analysed. Results ABI and EFT were significantly correlated with SS (r = -0.525, p < 0.001, and r = 0.650, p < 0.001, respectively) and found to be independent predictors of SS. ABI<0.9 mm identified patients with SS>22 with a sensitivity of 45.28% and a specificity of %82.64 (AUC = 0.689, %95 CI = 0.619-0.763, p<0.001). The optimal cutoff value for EFT was 5 mm, yielding a sensitivity of 81.1% and a specificity of 90.3% (AUC = 0.859, 95% CI 0.802–0.904). In order to identify which parameters were the most accurate, we compared both AUC of ROC curves and there was no difference (p = 0.170). Conclusion EFT and ABI enables the noninvasive prediction of CAD severity in patients with suspected CAD and combining ABI to EFT was additive for the prediction of coronary artery disease complexity.</description><subject>Adipose Tissue - diagnostic imaging</subject><subject>Adipose Tissue - pathology</subject><subject>Aged</subject><subject>Angiography</subject><subject>Ankle Brachial Index</subject><subject>Cardiovascular</subject><subject>Coronary</subject><subject>Coronary Angiography</subject><subject>Coronary Artery Disease - diagnosis</subject><subject>Epicardial fat thickness</subject><subject>Female</subject><subject>Humans</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Pericardium - diagnostic imaging</subject><subject>Pericardium - pathology</subject><subject>Peripheral artery disease</subject><subject>Prospective Studies</subject><subject>Severity of Illness Index</subject><subject>SYNTAX</subject><issn>1443-9506</issn><issn>1444-2892</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2014</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9Uk2LFDEUbERx19Uf4EVy9NK9-er0NIIwzn64sKDgCt5COnlxMtOTjEladn6E_9n0zurBg5e88KgqeFVVVa8Jbggm4nzTrEfdUEx4g1mDcfekOiWc85ouevr04c_qvsXipHqR0gZj0nHWP69OKO8w52JxWv1a-u0I6ENUeu3UiG68gfvyZvDJWQcJ5TWgC6e--5Cy02ip9VTABxQsutw7raKZeVcqo7u101sPKSEb4gPvcwTjdHbBz_BViMGreEDLmKGMC5dAJSj73X6Ee5cPL6tnVo0JXj3Os-rr1eXd6mN9--n6ZrW8rXXLea55Z0xHhkExvRA9DGAVbg21wgykHYa25VRQZfQwcMXaHiwGZbu2MDTrSCfYWfX2qLuP4ccEKcudSxrGUXkIU5Kk5b1gQix4gZIjVMeQUgQr99HtyhWSYDmnIDeypCDnFCRmsqRQOG8e5adhB-Yv44_tBfDuCIBy5E8HUSbtwOviVgSdpQnuv_Lv_2Hr0fkSxbiFA6RNmKIv7kkiE5VYfplrMLeA8NIASr-x31OEr3o</recordid><startdate>20140801</startdate><enddate>20140801</enddate><creator>Aykan, Ahmet Çağrı, MD</creator><creator>Gül, İlker, MD</creator><creator>Gökdeniz, Tayyar, MD</creator><creator>Hatem, Engin, MD</creator><creator>Arslan, Ahmet Oğuz, MD</creator><creator>Kalaycıoğlu, Ezgi, MD</creator><creator>Turan, Turhan, MD</creator><creator>Belen, Erdal, MD</creator><creator>Çetin, Mustafa, MD</creator><general>Elsevier B.V</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20140801</creationdate><title>Ankle Brachial Index Intensifies the Diagnostic Accuracy of Epicardial Fat Thickness for the Prediction of Coronary Artery Disease Complexity</title><author>Aykan, Ahmet Çağrı, MD ; Gül, İlker, MD ; Gökdeniz, Tayyar, MD ; Hatem, Engin, MD ; Arslan, Ahmet Oğuz, MD ; Kalaycıoğlu, Ezgi, MD ; Turan, Turhan, MD ; Belen, Erdal, MD ; Çetin, Mustafa, MD</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c544t-47dd71bba3c869ebefa05d2f6db15bb554262adcbb4a359ef0eaf751bbc371763</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2014</creationdate><topic>Adipose Tissue - diagnostic imaging</topic><topic>Adipose Tissue - pathology</topic><topic>Aged</topic><topic>Angiography</topic><topic>Ankle Brachial Index</topic><topic>Cardiovascular</topic><topic>Coronary</topic><topic>Coronary Angiography</topic><topic>Coronary Artery Disease - diagnosis</topic><topic>Epicardial fat thickness</topic><topic>Female</topic><topic>Humans</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Pericardium - diagnostic imaging</topic><topic>Pericardium - pathology</topic><topic>Peripheral artery disease</topic><topic>Prospective Studies</topic><topic>Severity of Illness Index</topic><topic>SYNTAX</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Aykan, Ahmet Çağrı, MD</creatorcontrib><creatorcontrib>Gül, İlker, MD</creatorcontrib><creatorcontrib>Gökdeniz, Tayyar, MD</creatorcontrib><creatorcontrib>Hatem, Engin, MD</creatorcontrib><creatorcontrib>Arslan, Ahmet Oğuz, MD</creatorcontrib><creatorcontrib>Kalaycıoğlu, Ezgi, MD</creatorcontrib><creatorcontrib>Turan, Turhan, MD</creatorcontrib><creatorcontrib>Belen, Erdal, MD</creatorcontrib><creatorcontrib>Çetin, Mustafa, MD</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Heart, lung & circulation</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Aykan, Ahmet Çağrı, MD</au><au>Gül, İlker, MD</au><au>Gökdeniz, Tayyar, MD</au><au>Hatem, Engin, MD</au><au>Arslan, Ahmet Oğuz, MD</au><au>Kalaycıoğlu, Ezgi, MD</au><au>Turan, Turhan, MD</au><au>Belen, Erdal, MD</au><au>Çetin, Mustafa, MD</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Ankle Brachial Index Intensifies the Diagnostic Accuracy of Epicardial Fat Thickness for the Prediction of Coronary Artery Disease Complexity</atitle><jtitle>Heart, lung & circulation</jtitle><addtitle>Heart Lung Circ</addtitle><date>2014-08-01</date><risdate>2014</risdate><volume>23</volume><issue>8</issue><spage>764</spage><epage>771</epage><pages>764-771</pages><issn>1443-9506</issn><eissn>1444-2892</eissn><abstract>Objectives Epicardial fat thickness (EFT) and Ankle brachial index (ABI) are associated with coronary artery disease (CAD). The SYNTAX score (SS) reflects the complexity of CAD. We aimed to evaluate the relation of EFT and ABI with CAD complexity. Methods We enrolled 197 patients undergoing coronary angiography. In all patients, ABI and EFT were determined. SS was calculated. The relationship between EFT, ABI and SS was analysed. Results ABI and EFT were significantly correlated with SS (r = -0.525, p < 0.001, and r = 0.650, p < 0.001, respectively) and found to be independent predictors of SS. ABI<0.9 mm identified patients with SS>22 with a sensitivity of 45.28% and a specificity of %82.64 (AUC = 0.689, %95 CI = 0.619-0.763, p<0.001). The optimal cutoff value for EFT was 5 mm, yielding a sensitivity of 81.1% and a specificity of 90.3% (AUC = 0.859, 95% CI 0.802–0.904). In order to identify which parameters were the most accurate, we compared both AUC of ROC curves and there was no difference (p = 0.170). Conclusion EFT and ABI enables the noninvasive prediction of CAD severity in patients with suspected CAD and combining ABI to EFT was additive for the prediction of coronary artery disease complexity.</abstract><cop>Australia</cop><pub>Elsevier B.V</pub><pmid>24704468</pmid><doi>10.1016/j.hlc.2014.03.007</doi><tpages>8</tpages></addata></record> |
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| subjects | Adipose Tissue - diagnostic imaging Adipose Tissue - pathology Aged Angiography Ankle Brachial Index Cardiovascular Coronary Coronary Angiography Coronary Artery Disease - diagnosis Epicardial fat thickness Female Humans Male Middle Aged Pericardium - diagnostic imaging Pericardium - pathology Peripheral artery disease Prospective Studies Severity of Illness Index SYNTAX |
| title | Ankle Brachial Index Intensifies the Diagnostic Accuracy of Epicardial Fat Thickness for the Prediction of Coronary Artery Disease Complexity |
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