Enhancement of Endothelial Function Inhibits Left Atrial Thrombi Development in an Animal Model of Spontaneous Left Atrial Thrombosis

Background:Left atrial (LA) thrombosis is an important cause of systemic embolization. The SPORTS rat model of LA thrombi (Spontaneously-Running Tokushima-Shikoku), which have a unique characteristic of high voluntary wheel running, was previously established. The aim of the present study was to inv...

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Veröffentlicht in:	Circulation Journal 2014/07/25, Vol.78(8), pp.1980-1988
Hauptverfasser:	Mawatari, Kazuaki, Yoshioka, Emiko, Toda, Satomi, Yasui, Sonoko, Furukawa, Hiroko, Shimohata, Takaaki, Ohnishi, Takamasa, Morishima, Masaki, Harada, Nagakatsu, Takahashi, Akira, Sakaue, Hiroshi, Nakaya, Yutaka
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Atrial fibrillation Disease Models, Animal Endothelial dysfunction Endothelium - metabolism Endothelium - pathology Female Heart Atria - metabolism Male Nitric oxide Nitric Oxide - metabolism Nitric Oxide Synthase Type III - metabolism Rats Thrombosis Thrombosis - metabolism Thrombosis - pathology Vasodilation
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