Macrophage Phenotypes and Their Modulation in Atherosclerosis

Atherosclerosis is the result of a chronic inflammatory response in the arterial wall related to uptake of low-density lipoprotein by macrophages and their subsequent transformation in foam cells. Monocyte-derived macrophages are the principal mediators of tissue homeostasis and repair, response to...

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Veröffentlicht in:	Circulation Journal 2014/07/25, Vol.78(8), pp.1775-1781
Hauptverfasser:	Paoli, Federica De, Staels, Bart, Chinetti-Gbaguidi, Giulia
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Atherosclerosis Atherosclerosis - immunology Atherosclerosis - pathology Humans Lipoproteins, HDL - immunology Macrophage phenotypes Macrophages - classification Macrophages - immunology Macrophages - pathology MicroRNAs - immunology Modulators Th1 Cells - immunology Th1 Cells - pathology Th2 Cells - immunology Th2 Cells - pathology Thioredoxins - immunology TOR Serine-Threonine Kinases - immunology Transcription Factors - immunology
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