Different Doses of Recombinant Tissue-Type Plasminogen Activator for Acute Stroke in Chinese Patients

BACKGROUND AND PURPOSE—The relationship between the dose of recombinant tissue-type plasminogen activator (r-tPA) and its safety/efficacy for ischemic stroke has not been well evaluated in the East Asian population. We assessed the safety/efficacy of different doses of r-tPA for acute ischemic strok...

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Veröffentlicht in:	Stroke (1970) 2014-08, Vol.45 (8), p.2359-2365
Hauptverfasser:	Chao, A-Ching, Liu, Ching-Kuan, Chen, Chih-Hung, Lin, Huey-Juan, Liu, Chung-Hsiang, Jeng, Jiann-Shing, Hu, Chaur-Jong, Chung, Chih-Ping, Hsu, Hung-Yi, Sheng, Wen-Yung, Hu, Han-Hwa
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Aged, 80 and over Asian Continental Ancestry Group Biological and medical sciences Blood. Blood coagulation. Reticuloendothelial system Brain Ischemia - drug therapy Dose-Response Relationship, Drug Female Fibrinolytic Agents - administration & dosage Fibrinolytic Agents - adverse effects Fibrinolytic Agents - therapeutic use Humans Infusions, Intravenous Male Medical sciences Middle Aged Neurology Pharmacology. Drug treatments Prospective Studies Stroke - drug therapy Thrombolytic Therapy - adverse effects Thrombolytic Therapy - methods Time Factors Tissue Plasminogen Activator - administration & dosage Tissue Plasminogen Activator - adverse effects Tissue Plasminogen Activator - therapeutic use Treatment Outcome Vascular diseases and vascular malformations of the nervous system
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