Effects of Deferoxamine on the Repair Ability of Dental Pulp Cells In Vitro

Abstract Introduction In previous studies, we found that hypoxia promoted the mineralization of dental pulp cells (DPCs). However, the clinical application of hypoxia as a therapy is questionable or unfeasible. Deferoxamine (DFO), a medication for iron overload, has also been shown to induce hypoxia...

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Veröffentlicht in:	Journal of endodontics 2014-08, Vol.40 (8), p.1100-1104
Hauptverfasser:	Jiang, Long, DDS, PhD, Peng, Wei-Wei, DDS, MDS, Li, Li-Fen, DDS, PhD, Du, Rong, DDS, PhD, Wu, Tian-Tian, DDS, MDS, Zhou, Zhuo-Jun, DDS, MDS, Zhao, Jun-Jun, DDS, PhD, Yang, Ya, DDS, PhD, Qu, Dong-Lin, BDS, Zhu, Ya-Qin, DDS, PhD
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Alkaline Phosphatase - analysis Calcification, Physiologic - drug effects Cell Culture Techniques Cell Differentiation - drug effects Cell Hypoxia - drug effects Cell Movement - drug effects Cell Proliferation - drug effects Cell Survival - drug effects Cells, Cultured Coloring Agents Deferoxamine Deferoxamine - pharmacology Dental Pulp - cytology Dental Pulp - drug effects dental pulp cells Dentistry Endocrinology & Metabolism Fluorescent Dyes Humans Hypoxia-Inducible Factor 1, alpha Subunit - analysis hypoxia-inducible factors-1α Odontoblasts - drug effects Osteocalcin - analysis Regeneration - drug effects repair ability Siderophores - pharmacology Tetrazolium Salts Thiazoles Young Adult
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