Switching Patients from Clopidogrel to Prasugrel in Acute Coronary Syndrome: Impact of the Clopidogrel Loading Dose on Platelet Reactivity

Objectives The present study aimed to assess the pharmacodynamic response of a prasugrel 60‐mg loading dose (LD) alone compared with prasugrel 60 mg added to clopidogrel 600 mg. Background Patients with acute coronary syndrome (ACS) undergoing percutaneous coronary intervention (PCI) commonly receiv...

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Veröffentlicht in:	Journal of interventional cardiology 2014-08, Vol.27 (4), p.365-372
Hauptverfasser:	LHERMUSIER, THIBAULT, LIPINSKI, MICHAEL J., DRENNING, DAVID, MARSO, STEVEN, CHEN, FANG, TORGUSON, REBECCA, WAKSMAN, RON
Format:	Artikel
Sprache:	eng
Schlagworte:	Acute Coronary Syndrome - therapy Dose-Response Relationship, Drug Female Humans Male Middle Aged Percutaneous Coronary Intervention Platelet Activation - drug effects Platelet Aggregation - drug effects Platelet Aggregation Inhibitors - administration & dosage Prasugrel Hydrochloride - administration & dosage Ticlopidine - administration & dosage Ticlopidine - analogs & derivatives
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