AUTONOMY: The First Randomized Trial Comparing Two Patient-Driven Approaches to Initiate and Titrate Prandial Insulin Lispro in Type 2 Diabetes

To compare two self-titration algorithms for initiating and escalating prandial insulin lispro in patients with type 2 diabetes inadequately controlled on basal insulin. The trial was designed as two independent, multinational, parallel, open-label studies (A and B), identical in design, to provide...

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Veröffentlicht in:	Diabetes care 2014-08, Vol.37 (8), p.2132-2140
Hauptverfasser:	EDELMAN, Steve V, RONG LIU, JOHNSON, Jennal, GLASS, Leonard C
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Aged Aged, 80 and over Algorithms Biological and medical sciences Blood Glucose - drug effects Body Weight - drug effects Clinical trials Comparative analysis Diabetes Diabetes Mellitus, Type 2 - blood Diabetes Mellitus, Type 2 - drug therapy Diabetes. Impaired glucose tolerance Endocrine pancreas. Apud cells (diseases) Endocrinopathies Etiopathogenesis. Screening. Investigations. Target tissue resistance Female Glycated Hemoglobin A - metabolism Humans Hypoglycemia Hypoglycemia - chemically induced Hypoglycemic Agents - administration & dosage Hypoglycemic Agents - adverse effects Insulin Insulin Glargine Insulin Lispro - administration & dosage Insulin Lispro - adverse effects Insulin, Long-Acting - administration & dosage Male Medical sciences Metabolic diseases Middle Aged Product safety Treatment Outcome Young Adult
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