Sialic Acids Sweeten a Tumor's Life

Over four decades ago, specific tumor characteristics were ascribed to the increased expression of sialic acid sugars on the surface of cancer cells, and this led to the definition of sialic acids as potential therapeutic targets. Recent advances in glycobiology and cancer research have defined the...

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Veröffentlicht in:	Cancer research (Chicago, Ill.) Ill.), 2014-06, Vol.74 (12), p.3199-3204
Hauptverfasser:	BÜLL, Christian, STOEL, Marieke A, DEN BROK, Martijn H, ADEMA, Gosse J
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antineoplastic agents Apoptosis Biological and medical sciences Disease Progression Drug Resistance, Neoplasm Glycosylation Humans Medical sciences Multiple tumors. Solid tumors. Tumors in childhood (general aspects) Neoplasm Metastasis Neoplasms - metabolism Neoplasms - pathology Neoplasms - therapy Pharmacology. Drug treatments Protein Processing, Post-Translational Radiation Tolerance Sialic Acids - metabolism Tumors
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