An Integrated Approach for Establishing Dosing Recommendations: Paliperidone for the Treatment of Adolescent Schizophrenia

The Food and Drug Administration recently approved Invega for the treatment of schizophrenia in adolescents 12 to 17 years. If dosing recommendations for this population would have been based only on the results of the single efficacy trial included in this program, paliperidone dosing in adolescent...

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Veröffentlicht in:	Journal of clinical psychopharmacology 2013-04, Vol.33 (2), p.152-156
Hauptverfasser:	YOUNIS, Islam Rasem, LAUGHREN, Thomas P, YANING WANG, MATHIS, Mitchell, GOBBURU, Jogarao V
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult and adolescent clinical studies Age Factors Antipsychotic Agents - administration & dosage Antipsychotic Agents - therapeutic use Biological and medical sciences Child Computer Simulation Dose-Response Relationship, Drug Double-Blind Method Drug Approval Follow-Up Studies Humans Isoxazoles - administration & dosage Isoxazoles - therapeutic use Medical sciences Models, Biological Neuropharmacology Paliperidone Palmitate Pharmacology. Drug treatments Psychoanaleptics: cns stimulant, antidepressant agent, nootropic agent, mood stabilizer Psychoanaleptics: cns stimulant, antidepressant agent, nootropic agent, mood stabilizer..., (alzheimer disease) Psycholeptics: tranquillizer, neuroleptic Psychology. Psychoanalysis. Psychiatry Psychopathology. Psychiatry Psychopharmacology Psychoses Pyrimidines - administration & dosage Pyrimidines - therapeutic use Schizophrenia Schizophrenia - drug therapy United States United States Food and Drug Administration
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