Metformin inhibits hepatitis B virus protein production and replication in human hepatoma cells

Summary Hepatitis B virus surface antigen (HBsAg) plays an important role in maintaining the tolerance and may interfere with host innate and adaptive immune responses; therefore, novel therapeutic strategies to reduce HBsAg loads in patients infected with hepatitis B virus (HBV) are emerging as an...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Journal of viral hepatitis 2014-08, Vol.21 (8), p.597-603
Hauptverfasser:	Xun, Y.-H., Zhang, Y.-J., Pan, Q.-C., Mao, R.-C., Qin, Y.-L., Liu, H.-Y., Zhang, Y.-M., Yu, Y.-S., Tang, Z.-H., Lu, M.-J., Zang, G.-Q., Zhang, J.-M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Antiviral Agents - pharmacology Drug Repositioning Hep G2 Cells Hepatitis B Surface Antigens - biosynthesis Hepatitis B virus hepatitis B virus (HBV) surface antigen Hepatitis B virus - drug effects Hepatitis B virus - physiology Hepatocytes - virology Humans metformin Metformin - pharmacology production transcriptional regulation Virus Replication - drug effects
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!