Vascular Risk in Migraineurs: Interaction of Endothelial and Cortical Excitability Factors
Background Migraine is a common primary headache disorder occurring predominantly in a young, relatively healthy population. Results There is a growing literature on associations between migraine, especially migraine with aura, and ischemic stroke as well as other vascular events. Migraine as a risk...
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| Veröffentlicht in: | Headache 2014-03, Vol.54 (3), p.583-590 |
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| container_title | Headache |
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| creator | Murinova, Natalia Krashin, Daniel L. Lucas, Sylvia |
| description | Background
Migraine is a common primary headache disorder occurring predominantly in a young, relatively healthy population.
Results
There is a growing literature on associations between migraine, especially migraine with aura, and ischemic stroke as well as other vascular events. Migraine as a risk factor for vascular disease and connections between migraine and endothelial, structural, and genetic risk are reviewed.
Conclusion
There may be an interaction between endothelial dysfunction and cortical spreading depression affecting risk. Patient education and treatment of modifiable risk factors may decrease future vascular events. |
| doi_str_mv | 10.1111/head.12304 |
| format | Article |
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Migraine is a common primary headache disorder occurring predominantly in a young, relatively healthy population.
Results
There is a growing literature on associations between migraine, especially migraine with aura, and ischemic stroke as well as other vascular events. Migraine as a risk factor for vascular disease and connections between migraine and endothelial, structural, and genetic risk are reviewed.
Conclusion
There may be an interaction between endothelial dysfunction and cortical spreading depression affecting risk. Patient education and treatment of modifiable risk factors may decrease future vascular events.</description><identifier>ISSN: 0017-8748</identifier><identifier>EISSN: 1526-4610</identifier><identifier>DOI: 10.1111/head.12304</identifier><identifier>PMID: 24512140</identifier><language>eng</language><publisher>United States: Blackwell Publishing Ltd</publisher><subject>Cerebrovascular Disorders - complications ; Cerebrovascular Disorders - epidemiology ; Cerebrovascular Disorders - physiopathology ; coronary artery disease ; Cortical Spreading Depression - physiology ; Drug therapy ; endothelial dysfunction ; Health risk assessment ; Humans ; hypercoagulable state ; migraine ; Migraine Disorders - complications ; Migraine Disorders - epidemiology ; Migraine Disorders - physiopathology ; Risk Factors ; Stroke</subject><ispartof>Headache, 2014-03, Vol.54 (3), p.583-590</ispartof><rights>2014 American Headache Society</rights><rights>2014 American Headache Society.</rights><rights>Copyright © 2014 American Headache Society</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c4644-3c5cf4d3715ff62bae85a6a9e7a425020ab4073466dc1e1caba26aed6574fd183</citedby><cites>FETCH-LOGICAL-c4644-3c5cf4d3715ff62bae85a6a9e7a425020ab4073466dc1e1caba26aed6574fd183</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1111%2Fhead.12304$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1111%2Fhead.12304$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,778,782,1414,27911,27912,45561,45562</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/24512140$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Murinova, Natalia</creatorcontrib><creatorcontrib>Krashin, Daniel L.</creatorcontrib><creatorcontrib>Lucas, Sylvia</creatorcontrib><title>Vascular Risk in Migraineurs: Interaction of Endothelial and Cortical Excitability Factors</title><title>Headache</title><addtitle>Headache: The Journal of Head and Face Pain</addtitle><description>Background
Migraine is a common primary headache disorder occurring predominantly in a young, relatively healthy population.
Results
There is a growing literature on associations between migraine, especially migraine with aura, and ischemic stroke as well as other vascular events. Migraine as a risk factor for vascular disease and connections between migraine and endothelial, structural, and genetic risk are reviewed.
Conclusion
There may be an interaction between endothelial dysfunction and cortical spreading depression affecting risk. Patient education and treatment of modifiable risk factors may decrease future vascular events.</description><subject>Cerebrovascular Disorders - complications</subject><subject>Cerebrovascular Disorders - epidemiology</subject><subject>Cerebrovascular Disorders - physiopathology</subject><subject>coronary artery disease</subject><subject>Cortical Spreading Depression - physiology</subject><subject>Drug therapy</subject><subject>endothelial dysfunction</subject><subject>Health risk assessment</subject><subject>Humans</subject><subject>hypercoagulable state</subject><subject>migraine</subject><subject>Migraine Disorders - complications</subject><subject>Migraine Disorders - epidemiology</subject><subject>Migraine Disorders - physiopathology</subject><subject>Risk Factors</subject><subject>Stroke</subject><issn>0017-8748</issn><issn>1526-4610</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2014</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqNkU1rFTEUhoMo9lrd-AMk4KYIU_NxkkzdlevtB1bFolbchDOZjE07d1KTGdr775vrbbtwIZ7N4cDzPnB4CXnJ2S4v8_bcY7vLhWTwiMy4EroCzdljMmOMm6o2UG-RZzlfMMZA7-mnZEuA4oIDm5Gf3zG7qcdET0O-pGGgH8OvhGHwU8rv6PEw-oRuDHGgsaOLoY3jue8D9hSHls5jGoMrx-LGhRGb0IdxRQ9KIKb8nDzpsM_-xd3eJt8OFl_nR9XJ58Pj-f5J5UADVNIp10ErDVddp0WDvlaocc8bBKGYYNgAMxK0bh333GGDQqNvtTLQtbyW22Rn471K8ffk82iXITvf9zj4OGXLFZgadHH8B8rASFXD2vr6L_QiTmkojxRKMiE0r3mh3mwol2LOyXf2KoUlppXlzK7Lsety7J9yCvzqTjk1S98-oPdtFIBvgOvQ-9U_VPZosf_-XlptMiGP_uYhg-nSaiONsmefDq2oz8SXDz9OrZG3ImGnZg</recordid><startdate>201403</startdate><enddate>201403</enddate><creator>Murinova, Natalia</creator><creator>Krashin, Daniel L.</creator><creator>Lucas, Sylvia</creator><general>Blackwell Publishing Ltd</general><general>Wiley Subscription Services, Inc</general><scope>BSCLL</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7TK</scope><scope>7U7</scope><scope>C1K</scope><scope>K9.</scope><scope>7X8</scope></search><sort><creationdate>201403</creationdate><title>Vascular Risk in Migraineurs: Interaction of Endothelial and Cortical Excitability Factors</title><author>Murinova, Natalia ; Krashin, Daniel L. ; Lucas, Sylvia</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4644-3c5cf4d3715ff62bae85a6a9e7a425020ab4073466dc1e1caba26aed6574fd183</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2014</creationdate><topic>Cerebrovascular Disorders - complications</topic><topic>Cerebrovascular Disorders - epidemiology</topic><topic>Cerebrovascular Disorders - physiopathology</topic><topic>coronary artery disease</topic><topic>Cortical Spreading Depression - physiology</topic><topic>Drug therapy</topic><topic>endothelial dysfunction</topic><topic>Health risk assessment</topic><topic>Humans</topic><topic>hypercoagulable state</topic><topic>migraine</topic><topic>Migraine Disorders - complications</topic><topic>Migraine Disorders - epidemiology</topic><topic>Migraine Disorders - physiopathology</topic><topic>Risk Factors</topic><topic>Stroke</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Murinova, Natalia</creatorcontrib><creatorcontrib>Krashin, Daniel L.</creatorcontrib><creatorcontrib>Lucas, Sylvia</creatorcontrib><collection>Istex</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Neurosciences Abstracts</collection><collection>Toxicology Abstracts</collection><collection>Environmental Sciences and Pollution Management</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>MEDLINE - Academic</collection><jtitle>Headache</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Murinova, Natalia</au><au>Krashin, Daniel L.</au><au>Lucas, Sylvia</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Vascular Risk in Migraineurs: Interaction of Endothelial and Cortical Excitability Factors</atitle><jtitle>Headache</jtitle><addtitle>Headache: The Journal of Head and Face Pain</addtitle><date>2014-03</date><risdate>2014</risdate><volume>54</volume><issue>3</issue><spage>583</spage><epage>590</epage><pages>583-590</pages><issn>0017-8748</issn><eissn>1526-4610</eissn><abstract>Background
Migraine is a common primary headache disorder occurring predominantly in a young, relatively healthy population.
Results
There is a growing literature on associations between migraine, especially migraine with aura, and ischemic stroke as well as other vascular events. Migraine as a risk factor for vascular disease and connections between migraine and endothelial, structural, and genetic risk are reviewed.
Conclusion
There may be an interaction between endothelial dysfunction and cortical spreading depression affecting risk. Patient education and treatment of modifiable risk factors may decrease future vascular events.</abstract><cop>United States</cop><pub>Blackwell Publishing Ltd</pub><pmid>24512140</pmid><doi>10.1111/head.12304</doi><tpages>8</tpages><oa>free_for_read</oa></addata></record> |
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| ispartof | Headache, 2014-03, Vol.54 (3), p.583-590 |
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| source | MEDLINE; Wiley Online Library Journals Frontfile Complete |
| subjects | Cerebrovascular Disorders - complications Cerebrovascular Disorders - epidemiology Cerebrovascular Disorders - physiopathology coronary artery disease Cortical Spreading Depression - physiology Drug therapy endothelial dysfunction Health risk assessment Humans hypercoagulable state migraine Migraine Disorders - complications Migraine Disorders - epidemiology Migraine Disorders - physiopathology Risk Factors Stroke |
| title | Vascular Risk in Migraineurs: Interaction of Endothelial and Cortical Excitability Factors |
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