Non-linear assessment of anticancer activity of 17-picolyl and 17-picolinylidene androstane derivatives – Chemometric guidelines for further syntheses

[Display omitted] The present paper deals with prediction of cytotoxic activity of 17-picolyl and 17-picolinylidene androstane derivatives toward androgen receptor negative prostate cancer cell line (PC-3). The prediction was achieved applying artificial neural networks (ANNs) method on the basis of...

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Veröffentlicht in:European journal of pharmaceutical sciences 2014-10, Vol.62, p.258-266
Hauptverfasser: Kovačević, Strahinja Z., Podunavac-Kuzmanović, Sanja O., Jevrić, Lidija R., Djurendić, Evgenija A., Ajduković, Jovana J.
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Sprache:eng
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