Hypothermia and neonatal encephalopathy
Data from large randomized clinical trials indicate that therapeutic hypothermia, using either selective head cooling or systemic cooling, is an effective therapy for neonatal encephalopathy. Infants selected for cooling must meet the criteria outlined in published clinical trials. The implementatio...
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Veröffentlicht in: | Pediatrics (Evanston) 2014-06, Vol.133 (6), p.1146-1150 |
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creator | Papile, Lu-Ann Baley, Jill E Benitz, William Cummings, James Carlo, Waldemar A Eichenwald, Eric Kumar, Praveen Polin, Richard A Tan, Rosemarie C Wang, Kasper S |
description | Data from large randomized clinical trials indicate that therapeutic hypothermia, using either selective head cooling or systemic cooling, is an effective therapy for neonatal encephalopathy. Infants selected for cooling must meet the criteria outlined in published clinical trials. The implementation of cooling needs to be performed at centers that have the capability to manage medically complex infants. Because the majority of infants who have neonatal encephalopathy are born at community hospitals, centers that perform cooling should work with their referring hospitals to implement education programs focused on increasing the awareness and identification of infants at risk for encephalopathy, and the initial clinical management of affected infants. |
doi_str_mv | 10.1542/peds.2014-0899 |
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Infants selected for cooling must meet the criteria outlined in published clinical trials. The implementation of cooling needs to be performed at centers that have the capability to manage medically complex infants. 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Infants selected for cooling must meet the criteria outlined in published clinical trials. The implementation of cooling needs to be performed at centers that have the capability to manage medically complex infants. Because the majority of infants who have neonatal encephalopathy are born at community hospitals, centers that perform cooling should work with their referring hospitals to implement education programs focused on increasing the awareness and identification of infants at risk for encephalopathy, and the initial clinical management of affected infants.</description><subject>Asphyxia Neonatorum - diagnosis</subject><subject>Asphyxia Neonatorum - mortality</subject><subject>Asphyxia Neonatorum - therapy</subject><subject>Babies</subject><subject>Care and treatment</subject><subject>Clinical trials</subject><subject>Cooling</subject><subject>Cooperative Behavior</subject><subject>Encephalopathy</subject><subject>Follow-Up Studies</subject><subject>Health aspects</subject><subject>Hospitals, Community</subject><subject>Humans</subject><subject>Hypothermia</subject><subject>Hypothermia, Induced - methods</subject><subject>Hypoxia-Ischemia, Brain - congenital</subject><subject>Hypoxia-Ischemia, Brain - diagnosis</subject><subject>Hypoxia-Ischemia, Brain - mortality</subject><subject>Hypoxia-Ischemia, Brain - therapy</subject><subject>Infant, Newborn</subject><subject>Infant, Premature, Diseases - diagnosis</subject><subject>Infant, Premature, Diseases - mortality</subject><subject>Infant, Premature, Diseases - therapy</subject><subject>Infants</subject><subject>Interdisciplinary Communication</subject><subject>Pediatrics</subject><subject>Randomized Controlled Trials as Topic</subject><subject>Referral and Consultation</subject><subject>Risk Assessment</subject><subject>Survival Rate</subject><issn>0031-4005</issn><issn>1098-4275</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2014</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpdkD1PwzAQhi0EoqWwMqJKDLCk-NvxWFVAkSp1gdlynEubyk1CnEj03-PQwsB0wz333qMXoVuCZ0Rw-tRAHmYUE57gVOszNCZYpwmnSpyjMcaMJBxjMUJXIewwxlwoeolGlKeSEyXH6GF5aOpuC-2-tFNb5dMK6sp21k-hctBsra8b220P1-iisD7AzWlO0MfL8_timazWr2-L-SpxXKou0dhGj2iWa0scc6nIlKBSZrTI8ly7NHWkyIQrKMNSZHEpeCY0y0XcMQA2QY_H3KatP3sIndmXwYH3Nor1wcToGKiUxhG9_4fu6r6tol2kmJBS0h8qOVIb68GUlaurDr46V3sPGzBRfrE2c6aUSLnUIvKzI-_aOoQWCtO05d62B0Pw8J2aoXIzVG6GyuPB3Umjz_aQ_-G_HbNvvb96Bw</recordid><startdate>201406</startdate><enddate>201406</enddate><creator>Papile, Lu-Ann</creator><creator>Baley, Jill E</creator><creator>Benitz, William</creator><creator>Cummings, James</creator><creator>Carlo, Waldemar A</creator><creator>Eichenwald, Eric</creator><creator>Kumar, Praveen</creator><creator>Polin, Richard A</creator><creator>Tan, Rosemarie C</creator><creator>Wang, Kasper S</creator><general>American Academy of Pediatrics</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7TS</scope><scope>7U9</scope><scope>H94</scope><scope>K9.</scope><scope>M7N</scope><scope>NAPCQ</scope><scope>U9A</scope><scope>7X8</scope></search><sort><creationdate>201406</creationdate><title>Hypothermia and neonatal encephalopathy</title><author>Papile, Lu-Ann ; 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subjects | Asphyxia Neonatorum - diagnosis Asphyxia Neonatorum - mortality Asphyxia Neonatorum - therapy Babies Care and treatment Clinical trials Cooling Cooperative Behavior Encephalopathy Follow-Up Studies Health aspects Hospitals, Community Humans Hypothermia Hypothermia, Induced - methods Hypoxia-Ischemia, Brain - congenital Hypoxia-Ischemia, Brain - diagnosis Hypoxia-Ischemia, Brain - mortality Hypoxia-Ischemia, Brain - therapy Infant, Newborn Infant, Premature, Diseases - diagnosis Infant, Premature, Diseases - mortality Infant, Premature, Diseases - therapy Infants Interdisciplinary Communication Pediatrics Randomized Controlled Trials as Topic Referral and Consultation Risk Assessment Survival Rate |
title | Hypothermia and neonatal encephalopathy |
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