Photoactive antiviral and cytotoxic activities of synthetic thiophenes and their acetylenic derivatives

A total of 31 thiophenes were tested for phototoxicity against two membrane-containing viruses, and for cytotoxicity, in comparison with the known potent phototoxic thiophene α-terthienyl. Several compounds were more potent against viruses, but were much less cytotoxic than α-terthienyl. The key str...

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Veröffentlicht in:Chemosphere (Oxford) 1989, Vol.19 (8), p.1329-1343
Hauptverfasser: Hudson, J.B., Graham, E.A., Miki, N., Towers, G.H.N., Hudson, L.L., Rossi, R., Carpita, A., Neri, D.
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Sprache:eng
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