The role of neck dissection and postoperative adjuvant radiotherapy in cN0 patients with PNI-positive squamous cell carcinoma of the oral cavity

Summary Introduction Loco-regional recurrence is one of the main causes of treatment failure in patients with oral squamous cell carcinoma (OSCC). Perineural invasion (PNI) is widely accepted as an oncologic feature strongly associated with aggressive behavior, disease recurrence and poorer prognosi...

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Veröffentlicht in:	Oral oncology 2014-08, Vol.50 (8), p.753-758
Hauptverfasser:	Chatzistefanou, Ioannis, Lubek, Joshua, Markou, Konstantinos, Ord, Robert A
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Carcinoma, Squamous Cell - radiotherapy Carcinoma, Squamous Cell - surgery Carcinoma, Squamous Cell - therapy Dermatology Hematology, Oncology and Palliative Medicine Humans Medical sciences Mouth Neoplasms - radiotherapy Mouth Neoplasms - surgery Mouth Neoplasms - therapy Multiple tumors. Solid tumors. Tumors in childhood (general aspects) Neck Dissection Oral squamous cell carcinoma Otolaryngology Otorhinolaryngology. Stomatology Perineural invasion Prognosis Radiotherapy Radiotherapy, Adjuvant Recurrence Tumors Tumors of the skin and soft tissue. Premalignant lesions Upper respiratory tract, upper alimentary tract, paranasal sinuses, salivary glands: diseases, semeiology
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